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USB videodermatoscopes are a practical and affordable alternative for diagnosing skin conditions.

KLHL24-mutant stem cells help understand skin and heart disease.

This study introduced and validated new spectrophotometric methods to simultaneously determine finasteride and tadalafil in Entadfi™ capsules with high sensitivity and without interference from excipients.

This study reviews the role of the zinc finger protein CXXC5 in cellular signaling and its implications for cancer, discussing how its dysregulation is linked to various physiological and pathological processes, as well as potential therapies targeting CXXC5.

In this phase II clinical study, combining anlotinib with standard platinum-based chemotherapy showed promising outcomes and prognosis in treating extensive small-cell lung cancer, with high disease control and response rates.

In this case report, researchers describe a 22-year-old male with a unique presentation of Senior-Løken Syndrome due to a NPHP4 mutation, exhibiting atypical symptoms like cryptorchidism, alopecia, and potential syndromic overlap with Rothmund-Thomson Syndrome, suggesting complex genetic interactions and expanding the phenotypic spectrum of ciliopathies.

This study found that the K6/ODC transgenic mouse model is highly sensitive to identifying genotoxic carcinogens, showing 100% concordance with traditional rodent bioassays.

This study identified a new heterozygous mutation in the connexin 26 gene (c.263C>T; p.Ala88Val) in a premature neonate with KID syndrome, who later died from complications.

This study validated a precise and sensitive reverse phase high performance liquid chromatographic method for determining Finasteride and Tamsulosin concentrations in bulk and tablet forms, with satisfactory accuracy and reproducibility.

This study found that mice with a mutant CDP/Cux protein lacking the homeodomain showed severely impaired growth, high postnatal mortality, and reduced fertility, highlighting CDP/Cux's role in developmental regulation.

This study describes the development of the EUSCLE Core Set Questionnaire for cutaneous lupus erythematosus, designed to standardize data collection, facilitate epidemiological analysis, and guide diagnostic and therapeutic strategies across European centers.

In this case report, a novel Ayurvedic preparation of Catharanthus roseus, used alongside conventional chemotherapy, was associated with tumor stability and improved general health in a patient with advanced esophageal squamous cell carcinoma.

This overview describes the Dermatologic Surgery journal's comprehensive focus on cosmetic and reconstructive skin procedures, but it reports no new research findings.

In this study, three cases of Cronkhite-Canada syndrome revealed small bowel mucosal lesions, but these findings did not correlate with clinical symptoms or steroid treatment outcomes.

This report highlights four cases where squamous cell carcinoma was misdiagnosed in individuals with darker skin, emphasizing the challenges in accurate diagnosis for this population.

This study found that finasteride's solubility and bioavailability were improved when using a dimethyl-β-cyclodextrin inclusion complex compared to the drug alone.

PRO-C22 can help diagnose and monitor the severity of hidradenitis suppurativa.

This chapter highlights various commercial and open-source light sheet microscopy systems, detailing their rapid evolution and integration of multimodal technologies, with a focus on the ZEISS Lightsheet Z.1 system's advanced design for direct imaging and specialized sample mounting.

This study found that extracts from Cirsium japonicum var. spinossimum seeds are rich in polyphenols and flavonoids, demonstrating significant anti-inflammatory and cell proliferation effects in specific cell models, suggesting potential as a source for anti-inflammatory and anticancer agents.

This overview highlights the Dermatologic Surgery journal's comprehensive coverage of skin surgery procedures and techniques, but it reports no new research findings.

This case report describes chronic iron deficiency anemia in a patient with Cronkhite-Canada syndrome, highlighting the need for more data to guide treatment and cancer surveillance due to its rarity and mortality risk.

This study reviewed the genetic and phenotypic aspects of Olmsted syndrome, highlighting pathogenic mutations in TRPV3 and MBTPS2 genes and their association with specific skin manifestations like symmetrical keratoderma and hyperkeratotic plaques.

A cancer patient died from a severe skin reaction after taking the drug cetuximab.

This overview describes the Dermatologic Surgery journal's full coverage of skin surgery topics, including various surgical procedures, but it reports no new research findings.

This study isolated highly pure oleanolic and maslinic acids from olive milling residues, exploring their chemical reactions, including the formation of finasteride precursors.

This study reports a unique case of coinheritance of BRCA2 and CYLD pathogenic variants in a man with metastatic malignant cylindroma, suggesting that recognizing such genetic profiles in rare conditions can provide new treatment options, including the potential use of therapies targeting BRCA deficiency.

This study found that KSR1 is essential for v-Ha-ras-mediated skin tumor formation in mice but not for MT-driven mammary tumor genesis, suggesting its potential as a therapeutic target in Ras/MAPK signaling.

This review highlights the potential of integrating point-of-care testing with allele-specific amplification techniques like AS-PCR, AS-LAMP, and AS-RPA to improve the efficiency, accuracy, and affordability of genotyping single nucleotide polymorphisms associated with human diseases.