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Topical treatments can deliver active molecules to skin stem cells, potentially helping treat skin and hair disorders, including skin cancers and hair loss.

Rapamycin reduces skin cell growth and tumor development by affecting cell signaling in mice.

Autologous cellular micrografts improve hair density and thickness in the short term for androgenetic alopecia.

Lower SMAD2/3 activation predicts more severe skin cancer.

Most hair follicle stem cells do not protect their DNA by dividing it unevenly.

Matriptase is highly active in hair follicles and sebaceous glands, especially during hair growth phases.

Male hair loss is caused by inactive hair follicle stem cells.

Cannabinoid receptor-1 signaling is essential for the survival and growth of human hair follicle stem cells.

The document concludes that the immune-inhibitory environment of the hair follicle may prevent melanoma development.

Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.

Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.

Oxidative stress plays a significant role in vitiligo, and both skin and non-skin cells may be involved.

Vav2 and Vav3 proteins help control skin stem cell numbers and activity in both healthy and cancerous cells.

Hair loss in Androgenetic Alopecia is caused by genetics, aging, and lifestyle, leading to hair follicle shrinkage and related health risks.

Changing CDK4 levels affects the number of stem cells in mouse hair follicles.

Hair and skin can regenerate without bulge stem cells due to other compensating cells.

mTOR signaling helps activate hair stem cells by balancing out the suppression caused by BMP during hair growth.

Removing integrin α3β1 from hair stem cells lowers skin tumor growth by affecting CCN2 protein levels.

Blocking the Mitochondrial Pyruvate Carrier causes stress in hair follicles, which can be reduced by an ISR inhibitor.

Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.

Higher TGF-β signaling may increase skin cancer risk in organ transplant recipients.

Aconiti Ciliare Tuber extract may help hair grow by activating a specific cell signaling pathway.

Using polymeric micelles to deliver spironolactone topically could improve wound healing in skin affected by glucocorticoids.

β-catenin is essential for stem cell activation and proliferation in hair follicles.

MicroRNAs are important for hair growth regulation, with Dicer being crucial and Tarbp2 less significant.

Different types of stem cells and their environments are key to skin repair and maintenance.

New understanding of the causes of primary cicatricial alopecia has led to better diagnosis and potential new treatments.

Dicer is crucial for hair growth in mice.

Researchers successfully grew hair follicle stem cells from mice and humans, which could be useful for tissue engineering and regenerative medicine.

Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.