Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that pregnane derivatives with higher lipophilicity, like compound 9d, had stronger androgen receptor binding and greater antiandrogenic effects in rats, correlating relative binding affinity with log P values.

This study found that depletion of TACE in mouse hair follicles led to impaired stem cell maintenance and hair loss, implicating TACE and EGFR signaling in hair follicle stem cell homeostasis.

This preliminary study found that poplar seed hair fibers have promising properties for use as environmentally friendly, lightweight insulation, with similar thermal resistance to wool and polyester despite being slightly less effective than down.

This study validated a precise and sensitive reverse phase high performance liquid chromatographic method for determining Finasteride and Tamsulosin concentrations in bulk and tablet forms, with satisfactory accuracy and reproducibility.

This review highlights preclinical and clinical advancements in gene and cell therapies for epidermolysis bullosa and ichthyosis, noting a recently FDA-approved gene therapy for recessive dystrophic EB.

This study found that multipotent neural crest stem cells from hair follicles require a full set of reprogramming factors for induced pluripotent stem cell induction, similar to fibroblasts.

This study developed a precise and reliable UV spectrophotometric method for determining finasteride concentration in bulk and tablets, demonstrating strong linearity and accuracy.

This study identified 47 genetic variants with a higher frequency in centenarians compared to young controls in the Bulgarian population, suggesting potential associations with longevity.

This study identified two key epigenetic-related genes, HR and SMYD4, which may act as potential biomarkers in keloid disease, suggesting new therapeutic avenues for further research.

This study developed and validated a simple, cost-effective UV–Visible spectrophotometric method for estimating finasteride in pharmaceuticals, demonstrating good linearity, accuracy, precision, and sensitivity according to ICH guidelines, making it suitable for routine quality control.

This study observed that albino rats, despite not producing melanin, have melanocytes localized in specific skin areas of their hair matrix, suggesting that gene expression analysis of their skin should consider regional differences in melanocyte presence.

This study observed that herbal feed supplementation in Frieswal breeding bulls improved semen volume and motility, while significantly lowering dihydrotestosterone levels, suggesting a potential mechanism for enhancing semen quality.

This study validated a UV-spectrophotometric method for accurately detecting Minoxidil and Tofacitinib citrate concentrations in bulk and gel formulations for alopecia areata, showing high recovery rates and indicating the method's suitability for routine analysis.

This article presents a family case study of dermatopathia pigmentosa reticularis linked to a specific KRT14 gene variant, detailing symptoms and stressing the importance of molecular diagnosis for management.

This study observed unexpected heterogeneity among pigment cells in human scalp hair follicles, identifying immature melanocyte populations outside traditional pigment production zones, raising questions about their potential roles beyond melanin synthesis.

In this study, researchers explored the heterogeneity of pigment cells in the human scalp anagen hair follicle bulb and discovered unexpected subpopulations of melanocytes, including immature SOX10-negative cells, highlighting potential non-melanogenic roles or transitional migratory functions that require further investigation.

This study identified six species of ectoparasitic insects infesting domestic goats in Bulgaria, with Linognathus stenopsis being the most prevalent across the surveyed farms.

This study discusses the development of a turmeric-based herbal hair removal product named PASIKULA, highlighting its potential to increase the economic value of turmeric and acceptance by consumers.

The researchers reported that the OVOL1-OVOL2 axis may play a role in hair follicle differentiation and tumorigenesis, and OVOL1 and OVOL2 are potential diagnostic markers for pilomatricoma and pilomatrix carcinoma.

This study found that low levels of ferritin and iron were common among women with diffuse hair loss, suggesting these tests could be useful in evaluating such patients.

This case study describes a one-year-old female Pit Bull Terrier with alopecia X whose hair was fully restored after trilostane therapy addressed an adrenal sex hormone imbalance.

High blood pressure drugs often cause skin lupus, stopping the drug usually helps. A vaccine helps prevent genital herpes and HPV-16. More frequent light therapy clears psoriasis faster. No link was found between low iron and chronic hair loss.

This document supplements a study on androgenetic alopecia, describing materials and methods, and includes figures showing fibrosis in the bulge region of miniaturized hair follicles.

This pilot study suggests that skin-resident γδT-cells may play a significant role in the early stages of alopecia areata pathogenesis, indicating a potential new target for therapeutic management.

This study found that ATM protein plays a crucial role in protecting human hair follicle melanocytes from oxidative stress, which is linked to the greying of hair.

This research discusses a validated HPTLC method for simultaneously determining Tamsulosin Hydrochloride and Finasteride in bulk and pharmaceutical dosage forms but reports no new clinical results.

This study highlights the challenges adolescents with alopecia areata face, such as increased bullying and emotional difficulties, and suggests that collaborations among dermatologists, psychologists, and educators could help improve their quality of life by reducing stigma and supporting mental wellbeing.

This case report documented a novel presentation of a canine viral plaque appearing as a solitary exophytic keratin-filled mass, highlighting the need to differentiate it from a hair follicle tumor.