TLDR Trilostane treatment successfully restored hair growth in a dog with alopecia X.
This paper detailed the case of a one-year-old female American Pit Bull Terrier with progressive baldness diagnosed as alopecia X, a hormone-responsive dermatosis. Initial treatment with ovariohysterectomy led to temporary hair regrowth, but symptoms returned more severely. Further hormonal tests indicated an adrenal sex hormone imbalance, leading to trilostane therapy at 8 mg/kg/day, administered twice daily. This treatment resulted in complete hair regrowth within four months, with no adverse effects observed.
15 citations
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September 2005 in “The Journal of the American Animal Hospital Association/Journal of the American Animal Hospital Association” Trilostane effectively treated hair loss in Alaskan Malamutes with no adverse effects.
40 citations
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October 2004 in “Veterinary Dermatology” Trilostane treatment led to full hair regrowth in most Pomeranians and all miniature poodles with alopecia X.
149 citations
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June 2002 in “Veterinary record/The veterinary record” Trilostane effectively improved symptoms in dogs with a certain adrenal gland disorder.
581 citations
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October 1998 in “Journal of The American Academy of Dermatology” Finasteride safely and effectively treats male pattern hair loss, but may cause reversible sexual issues and harm male fetuses.
10 citations
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June 1998 in “PubMed” Finasteride significantly reduces DHT levels in male dogs without affecting testosterone levels, suggesting it could be used to treat benign prostatic hypertrophy in dogs weighing 10 to 50 kilograms.
