182 citations
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August 2016 in “Development” This review discusses the roles and mechanisms of chromatin remodelers and their subunits in mammalian development, but reports no new experimental results.
September 2026 in “Stem Cell Reviews and Reports” Bulge progenitor cells show promise for regenerating hair follicles and increasing hair density.
This study introduces a new type of tissue micromodule, the micro tissue precursor (μTP), which can form complex 3D tissues, including lung stroma and skin models supporting hair viability.
23 citations
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January 2016 in “Theranostics” In this animal study, ultrasound combined with a new microbubble formulation of minoxidil increased hair growth rates and improved follicle characteristics more effectively than minoxidil alone.
80 citations
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June 2008 in “Biomaterials” This study found that poly(ethylene-co-vinyl alcohol) membranes support the self-assembly of dermal papilla cells into compact spheroidal microtissues capable of inducing new hair follicles, suggesting potential for large-scale production for hair follicle regeneration.
59 citations
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March 1984 in “Journal of Investigative Dermatology”
26 citations
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August 2016 in “ACS Applied Materials & Interfaces” In this study, cell membrane remodeling with a thermoresponsive boronic acid copolymer was shown to rapidly form spheroids from cancer or cardiac cell lines under standard conditions, promising advances in tissue engineering.
12 citations
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May 2016 in “British Journal of Dermatology” This report describes a rare case of epidermolysis bullosa acquisita in a child developing during therapy with squaric acid dibutyl ester for alopecia areata, suggesting a possible link between the medication and disease onset.
July 2026 in “Research Data Repository, Duke University” This study observed that DMAP scaffolds in a full-thickness wound model promote dermal appendage regeneration by activating humoral immunity, specifically through B cell activation and antibody production, even when adaptive immune cells' infiltration is restricted.
January 2014 in “Jaypee Brothers Medical Publishers (P) Ltd. eBooks” Learn how to create and run a global hair-restoration business.
November 2025 in “Scientia Pharmaceutica” This review highlights that injectable biostimulatory agents like poly-L-lactic acid, polycaprolactone, and calcium hydroxyapatite are effective in regenerative aesthetics by enhancing collagen production, stimulating adipogenesis, and improving dermal quality, although further research is needed to standardize protocols and confirm long-term safety and efficacy.
8 citations
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October 2024 in “Developmental Cell”
This study found that hyaluronic acid increased the size of hair follicle germ-like aggregates and the number of proliferative cells but did not maintain specific markers during the process.
8 citations
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October 2022 in “Biomedical Materials” This study found that incorporating hair follicle-primed spheroids into skin constructs showed potential for developing hair-bearing skin mimetics with follicle-forming abilities in vitro.
16 citations
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January 2023 in “Regenerative Biomaterials” This study examined 3D-printed scaffolds coated with polydopamine and observed that they significantly enhanced osteogenesis and angiogenesis in vitro and in a rat cranium defect model, suggesting their potential for repairing large bone defects.
August 2023 in “Micromachines” In this study, researchers developed a multilayered gel bead culture model using a microgel-spotting device, successfully mimicking the early development of skin appendages and supporting in vitro hair follicle regeneration with structures resembling native hair follicles.
1 citations
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July 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that centrosome ablation in developing epidermis triggers cell surveillance pathways, resulting in thinner skin and halted hair follicle growth, while later stages of epidermal growth may operate independently of basal progenitor division orientation.
1 citations
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November 2022 in “Experimental cell research” This study found that a PGE2 matrix, when injected subcutaneously, increased the proportion of developing hair follicles and improved hair follicle stem cell markers in a mouse model of hair loss.
20 citations
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January 2022 in “Polymers” In this review, researchers reported that incorporating nanoparticles into natural-based biomaterials enhanced scaffolding properties, cellular interactions, and outcomes in wound healing, with promising implications for tissue engineering and regenerative medicine, although many signaling pathways involved are still not fully understood.
8 citations
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October 2021 in “Stem Cell Research & Therapy” This review examines the potential of mesenchymal stem/stromal cells in treating and possibly preventing allergic diseases, and reports no new clinical results.
2 citations
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May 2017 in “Archives of Plastic Surgery” This article explores the origins and differences between human and animal faces, emphasizing the face's role in communication and its relevance to plastic surgery, but presents no new research findings.
1 citations
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September 2024 in “Cosmetics” This study found that permanent makeup pigments were applied at similar depths as traditional tattoo inks in mice but faded over time due to larger inorganic pigments.
1 citations
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November 2022 in “International journal of molecular sciences” This study found that local injections of fetal tissue mesenchymal stromal cells in mice significantly improved healing and hair follicle density after high-dose radiation-induced skin damage.
March 2026 in “Biomedicines” This review synthesizes current evidence on therapies for dissecting cellulitis of the scalp, noting that biologics show promise for treatment-resistant cases, though systemic retinoids remain the first-line therapy.
June 2026 in “Journal of General-Procedural Dermatology & Venereology Indonesia” This review highlights that various components of "skin boosters," such as exosomes and hyaluronic acid, may have potential applications beyond aesthetics, acting as adjunct therapies for improving skin integrity and promoting tissue regeneration, though more research is needed to support their use as primary treatments.
42 citations
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January 2017 in “Stem cells international” This study found that while extracellular matrix components like hyaluronic acid promoted larger organoid formation, other matrix components hindered hair follicle germ assembly in an in vitro model.
4 citations
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June 2007 in “PubMed” This study found that using engineered skin with PGA-collagen scaffolds, combined with hair follicle stem cells and other cell types, effectively repaired full-thickness skin defects in nude mice.
5 citations
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November 2024 in “Advanced Science” This study reported the establishment of a chemically defined culture system that supports tooth reconstitution and detailed how co-stimulation of specific signaling pathways can sustain tooth development stages and initiate enamel formation, providing insights into tooth regeneration mechanisms.
7 citations
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January 2017 in “Sub-cellular biochemistry/Subcellular biochemistry”
This study developed and tested continuous implanters for dermal papilla cell aggregates, finding that the bar-cartridge type implanter is the most effective design for continuous cell implantation in androgenetic alopecia research.