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This study found that patients with Bachmann-Bupp syndrome treated with DFMO showed improvements in hair growth, muscle tone, and development.

Entadfi, a mix of finasteride and tadalafil, is used for BPH.

In this study, naringenin and its methylated derivatives reduced depression-like behaviors and inflammation markers in mice exposed to finasteride, suggesting their potential as effective and safe anti-depressive agents.

Finasteride significantly reduced tics and obsessive-compulsive symptoms in Tourette syndrome patients.

This study found that metyrapone and etomidate provide dose-dependent anticonvulsant effects against seizures, with delayed effectiveness linked to increased neurosteroid levels.

In this animal study, the researchers found that administering anionic lipid nanoemulsions called squarticles increased survival rates and mitigated the adverse effects of amitriptyline overdose in rats.

This study reviewed 16 notable drug repurposing patent applications from 2025, highlighting potential new uses such as guanfacine for autonomic dysfunction and disulfiram for subarachnoid hemorrhage survival, though many disclosures lack peer-reviewed studies and no patents are granted.

This study concluded that the anesthesia protocol using fentanyl, propofol, cisatracuria besylate, tranexamic acid, atropine, and metoclopramide resulted in the least pain during septoplasty.

This study found that Adiantum capillus-veneris extract exhibited significant antidepressant and anti-anxiety effects in rats, likely due to its antioxidant and anti-inflammatory properties.

This study evaluated methods to administer betulin in in vivo experiments and found that olive oil, food-grade lard, and other carriers increase betulin absorption in Wistar rats, while monitoring blood levels may aid future clinical research.

This study identified mefloquine as a potent inducer of lethal ER stress that effectively eliminated vemurafenib-resistant and sensitive melanoma cells, suggesting its potential for repurposing as a melanoma treatment.

In this study, baicalin from Scutellaria baicalensis decreased androgen levels in both cells and PCOS model rats by inhibiting key gene expression, suggesting it may be a potential treatment for hyperandrogenism in PCOS.

Man stopped medications due to sexual side effects, found relief with prostatic artery embolisation.

This source explores the potential use of oral bicalutamide for treating female pattern hair loss, but specific results or outcomes from the study are not reported in the abstract.

This study found that neurosteroids and benzodiazepines decrease network excitability in neuronal cultures, with specific long-term depressive effects on inhibitory neurons.

This case report suggests that discontinuing finasteride, which may affect neurosteroids synthesis, improved seizure control in a woman with temporal lobe seizures.

This review focuses on the pharmacological properties, indications, contraindications, and safety profile of bicalutamide, a non-steroidal androgen receptor antagonist, in dermatological research, particularly its off-label use for improving female pattern hair loss as measured by Sinclair grading.

This case report suggests that intradermal botulinum toxin type A may alleviate pruritus and reduce papules in Fox-Fordyce disease, improving quality of life without serious adverse effects for at least six months.

In this study involving ICR mice, researchers found that Korean red pine bark extract improved cognitive functions impaired by TMT through mechanisms like antioxidant system protection, cholinergic and synaptic support, mitochondrial regulation, and reduction of neuro-inflammation and apoptosis.

This case report from the University of Alabama describes a rare paradoxical effect where divalproex sodium was associated with increased agitation and hostility in a patient with schizoaffective disorder.

In this study, researchers found that the compound BMS-470539 induced a senescence-like state in fibroblasts from systemic sclerosis patients, reducing fibrosis-associated markers in vitro and decreasing skin thickness in a mouse model of skin fibrosis, suggesting a novel therapeutic strategy for managing fibroblast-driven diseases.

This animal study found that berberine may alleviate benign prostatic hyperplasia by reducing inflammation and oxidative stress through inhibition of the NF-κB signaling pathway.

This study found that PK11195 treatment weakened exploratory behavior in two strains of mice, while finasteride and indomethacin decreased exploration in laboratory rodents regardless of species.

This study reviewed the pharmacological properties of fesoterodine and found that its ability to effectively treat overactive bladder, especially in the elderly, is likely due to its specific properties, including its receptor affinity, blood-brain barrier penetration, metabolic conversion, and extended-release formulation.

In this study, brindled mutant mice with clinical features similar to kinky hair syndrome showed marked improvement and prevention of neuronal degeneration after receiving cupric chloride injections, with timing of administration being crucial.

This study found that a combination of betulin and cytostatic Namitecan had a statistically significant synergistic effect on solid Ehrlich adenocarcinoma tumors in NMRI mice, and suggests a promising method for administering betulin in in vivo experiments despite its water insolubility.

This study found that Caesalpinia bonduc seed extracts significantly reduced prostate weight and improved prostate tissue morphology in Wistar rats with testosterone-induced benign prostatic hyperplasia.

In this study, Tolterodine Tartrate significantly improved symptoms of overactive bladder and showed fewer adverse reactions compared to the control group treatment.