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This study explores how EGFR signaling impacts skin inflammation and follicular integrity during hair eruption, aiming to identify druggable pathways to mitigate skin inflammation in cancer patients receiving EGFR inhibitors.

In this study of male patients with non-curly hair, the researchers observed a significant occurrence of folliculitis nuchae linked to close haircuts and shaving, with treatment effectiveness varying by disease phase and best results seen in early stages.

New ways to treat acne are being discovered.

This genome-wide association study identified 20 genetic signals at 15 risk loci related to severe acne, revealing new insights into its genetic predisposition, particularly affecting skin structure and maintenance.

This review discusses common skin eruptions caused by biologics in treating inflammatory bowel disease and proposes tailored therapeutic approaches for managing these adverse reactions.

This article documents a case of acne vulgaris in a 23-year-old female patient and reports no new research findings.

This study introduced a surgical technique involving tweezers to effectively treat acne vulgaris, achieving complete healing in 99% of 4566 patients within up to 50 treatments, potentially reducing psychological distress and medication side effects.

This study reports that Iressa, an anti-cancer agent, commonly causes acneiform eruptions and xerosis as cutaneous side effects, similar to other agents targeting epidermal growth factor receptors.

Razor bumps are linked to a genetic variant, misoprostol helps erythromelalgia pain, steroid ointments don't affect skin rhythms, and certain antibodies are common in localized scleroderma.

This review of acne management strategies highlights current treatments, such as topical and systemic therapies, procedural methods, and dietary changes, while also discussing emerging options like biologics and probiotics as potential future treatments, emphasizing personalized care due to acne's complex nature.

This case report describes a 19-year-old male with alopecia totalis and comedones over the bald scalp, suggesting the importance of terminal hair for sebum drainage to prevent preliminary acne lesions.

This review discusses various drugs that can cause drug-induced acne, noting specific clinical and histopathologic features, but reports no new clinical findings.

Acne in children varies by age and severity, requires a pediatric treatment approach, and may need diagnostic evaluation for underlying conditions.

This study reported that EGFR inhibitor therapy in lung and head/neck cancer patients was associated with acneiform eruptions and severe skin dryness, which rarely necessitate discontinuation of treatment and can be managed symptomatically.

Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.

This review assessed dermo-cosmetic treatments using prebiotics, probiotics, synbiotics, and other biotics for acne and scalp disorders, finding potential benefits, especially with multi-strain or synbiotic formulations, although challenges like formulation stability and the need for larger trials persist.

This study found no evidence of increased keratinocyte proliferation in acne vulgaris, suggesting that other mechanisms may be responsible for hyperkeratinization in acne pathogenesis.

This study observed that adult female acne may be associated with hyperandrogenic features and polycystic ovary syndrome, though routine hormonal tests often do not show abnormalities other than PCOS.

In this study, skin manifestations such as hirsutism and acne were prevalent among women with PCOS, highlighting their importance in diagnosis and symptomatology.

The 7-month-old boy has a persistent rash that doesn't improve with typical skin treatments.

This report observed that two teenagers developed skin issues, including abscess-like pustules, after taking kelp supplements, which cleared when the supplements were discontinued.

This study found that acne was the most common dermatological manifestation in Korean women with polycystic ovary syndrome, particularly those with a specific combination of symptoms, showing distinct variations in serum hormonal and metabolic parameters.

Lactic acid cream can help improve skin bumps known as eruptive vellus hair cysts.

This abstract reviews recent findings on genetic factors in acne, highlighting the potential of genetic studies to advance understanding of its pathogenesis, but reports no new clinical results.

This study reports that ZD1839 (Iressa), an anticancer drug, was associated with acneiform eruptions and hair growth abnormalities due to its inhibition of epidermal growth factor receptor signaling in the skin.

A 16-year-old girl's skin rash was likely caused by an infection and improved with topical steroids.

In this study using a rat model, researchers observed that applying topical testosterone led to changes in the skin resembling early acne lesions, indicating a dermatologic risk potentially associated with over-the-counter testosterone products.

In this review, the authors examine current treatments for acne in adult women with polycystic ovarian syndrome, noting that the combination of hyperandrogenism and metabolic issues in PCOS can lead to acne formation on the face, chest, and back.

This mini review reports on papulopustular eruptions linked to classical EGFR inhibitors, MEK inhibitors, and amivantamab, highlighting distinct dermatologic toxicities in each treatment context and exploring underlying mechanisms and management strategies.

This study found that an acne complex animal model using rabbits showed more pronounced clinical symptoms and measured changes compared to the traditional Kligman model.