63 citations,
November 1999 in “British journal of dermatology/British journal of dermatology, Supplement” Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.
26 citations,
July 2012 in “Journal of family planning and reproductive health care” The document says that hirsutism in women usually needs hair removal and hormone treatment to manage symptoms and improve well-being.
January 2025 in “British Journal of Dermatology” Long scalp hair evolved for cooling and social signaling.
6 citations,
August 2020 in “Journal of Pharmaceutical Innovation” Nanoemulgel improves hair growth and quality using finasteride without irritation.
8 citations,
October 1998 in “Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology” Proscar (finasteride) blocks 5α-reductase in sea urchin ovaries and testes, suggesting potential treatment for androgen-related conditions.
54 citations,
June 1985 in “American Journal of Dermatopathology” Minoxidil helps grow longer, thicker hair in bald scalps of stumptailed macaques, and early treatment is more effective.
Thyroid problems can cause hair loss and change hair texture.
26 citations,
April 2019 in “Journal of Cosmetic Dermatology” Herbal alternatives like saw palmetto and green tea may offer safe, effective treatment for hormonal hair loss.
11 citations,
August 2007 in “Bioorganic & Medicinal Chemistry Letters” Scientists made a chemical (compound 4e) that can be applied on skin to reduce oil production, which can help with acne, but it might cause skin sensitivity to light.
27 citations,
July 2012 in “Dermatologic Surgery” Higher caspase-1 levels found in balding scalps; reducing it may help treat hair loss.
112 citations,
July 2012 in “The Journal of Sexual Medicine” Finasteride may cause long-lasting sexual side effects.
1 citations,
February 2017 in “MOJ bioequivalence & bioavailability” Treating hair loss effectively may require a multi-sided approach, using different treatments together, and topical treatments could be more effective and safer than oral ones.
20 citations,
August 2018 in “The World Journal of Men's Health” Finasteride may increase erectile dysfunction risk in patients with benign prostatic hyperplasia.
9 citations,
February 2005 in “The Journal of Men's Health & Gender” Finasteride effectively treats male hair loss, increasing length and thickness.
1 citations,
January 2017 in “Elsevier eBooks” The document concludes that new treatments for hair loss may involve a combination of cosmetics, clinical methods, and genetic approaches.
2 citations,
January 1997 in “Principles of Medical Biology” Drug metabolism affects how long a drug works, its interactions, activation, and toxicity, and is influenced by genetics, diet, illness, and other drugs.
10 citations,
January 2003 in “Seminars in reproductive medicine” The article explains how to identify and treat excessive hair growth in women, which can be distressing and may signal other health problems.
18 citations,
February 2018 in “International Journal of Molecular Sciences” PGD2 increases androgen receptor activity in hair cells, which could be targeted to treat hair loss.
43 citations,
January 1977 in “Toxicology and Applied Pharmacology” Minoxidil is mostly safe, but high doses can cause electrolyte imbalances and heart issues in dogs.
5 citations,
September 2012 in “Springer eBooks” Nanoparticles can be used to deliver drugs to hair follicles, potentially improving treatments for conditions like acne and alopecia, and could also be used for vaccine delivery and gene therapy.
50 citations,
October 2014 in “International Journal of Clinical Pharmacology and Therapeutics” New finasteride solution effectively reduces baldness-causing hormone, potentially with fewer side effects.
17 citations,
January 2020 in “The World Journal of Men's Health” Long-term use of finasteride and dutasteride can cause serious health issues like diabetes and liver problems.
5 citations,
June 2011 in “Bioorganic & Medicinal Chemistry Letters” New Finasteride conjugate improves prostate treatment and vital signs in rats.
153 citations,
November 2004 in “Current Medicinal Chemistry” The document concludes that Catalyst software is effective for drug design, identifying potent compounds for various medical conditions.
27 citations,
January 1984 in “Pharmacology & Therapeutics” Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.
60 citations,
April 2010 in “General and Comparative Endocrinology” Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.
13 citations,
March 2017 in “Genomics” Genomic approach finds new possible treatments for hair loss.
19 citations,
July 1990 in “Cleveland Clinic journal of medicine” Androgen excess disorders in women were effectively treated with spironolactone, estrogen, and dexamethasone.
1 citations,
May 2017 in “InTech eBooks” Some natural remedies may help with hair regrowth, but more research is needed to confirm their effectiveness and safety.
18 citations,
October 2018 in “Nutrients” Annurca apple extract promotes hair growth by changing hair follicle metabolism to boost keratin production.