2 citations
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June 2022 in “Phytomedicine” This study found that Shi-Bi-Man, a hair health supplement, significantly promoted hair growth in mice, likely through activation of the FGF signaling pathway.
September 2018 in “Epsilon Archive for Student Projects (University of Southampton)” This study found that treatment with Bacillus amyloliquefaciens UCMB5113 significantly increased root hair growth in half of the tested Arabidopsis thaliana accessions.
193 citations
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February 2015 in “Nature Communications” Fungi-produced compounds can change plant root growth.
52 citations
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May 2011 in “Journal of Neuroendocrinology” This study found that palmitoylethanolamide may stimulate allopregnanolone synthesis and reduce oxidative stress in astrocytes through PPAR-α activation, suggesting a neuroprotective role.
May 2025 in “Journal of Neonatal Surgery” This source discusses clinical studies on plant-derived growth factors for treating androgenic alopecia, highlighting their potential to stimulate hair follicle regeneration as an alternative to traditional therapies.
In this review, researchers evaluated 111 studies on the biological activities and phytochemical components of the plant Tridax procumbens, emphasizing its ethnobotanical potential and the need for more research to understand its therapeutic benefits, especially in its native tropical regions.
1 citations
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January 2013 in “Digital Scholarship - UNLV (University of Nevada Reno)” This study hypothesized that finasteride administration may increase stress-induced amphetamine locomotor sensitization due to its impact on brain reward systems involving the neurosteroid allopregnanolone.
January 2026 in “International Journal of Research in Pharmacy and Allied Science” In this study, researchers developed a herbal hair oil using natural ingredients like amla, hibiscus, and coconut oil, aiming to create a formulation with nourishing and antioxidant properties, while offering stability and safe use for scalp application.
This study evaluated 32 marker compounds from natural herbal extracts and found that four of them, honokiol, isoalantolactone, broussochalcone A, and 3-deoxysappanone B, can induce hair growth, suggesting a potential natural treatment for hair loss.
2 citations
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January 2009 This article reviews the development of a topical hair growth agent using natural extracts and reports no new clinical results, emphasizing the need for further evaluation of its efficacy.
October 2022 in “Research Square (Research Square)” This study found that volatile compounds from Bacillus subtilis strain WM13-24 improved root development in Arabidopsis by influencing auxin signaling.
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review critically evaluated natural hair growth actives for the 2025–2026 marketplace and found they show potential as alternatives to conventional therapies for androgenetic alopecia, with favorable safety and patient acceptance, though challenges such as formulation instability and limited follicular penetration remain.
92 citations
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September 2019 in “ACS nano” This study observed that a wearable electric stimulation device significantly promoted hair regeneration in rats and mice, outperforming conventional pharmacological treatments and enhancing growth factor secretion.
September 2025 in “PubMed” This review discusses recent advances in hair regeneration strategies, including mechanical stimulation and complementary therapies like MSC transplantation and platelet-rich plasma, and reports no new clinical results.
August 2026 in “International Journal of Molecular Sciences” This study found that Atractylodes macrocephala Koidz. extract promotes anagen entry and hair regrowth by enhancing dermal papilla cell activity and supporting hair cycle progression in a mouse model.
January 2026 in “Journal of Advanced Research” This study found that fermentation products from Bacillus sp. TC5 can effectively promote hair regrowth and improve transdermal drug absorption, suggesting their potential as eco-friendly agents in developing cosmeceuticals for hair restoration and skin repair.
1 citations
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October 2025 in “Journal of Microbiology and Biotechnology” This study suggests that phytochemicals from natural sources could be safer alternatives to conventional treatments for hair loss, as they may activate key pathways involved in hair growth.
8 citations
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July 2014 in “Hair transplant forum international” This article discusses key surgical techniques for optimal graft growth in hair transplantation and presents no new research findings.
4 citations
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January 2024 in “Environmental Research” In this study, the authors reported that Sargassum wightii seaweed-based biostimulants improved soil quality and enhanced rice plant growth and yield by ameliorating acid soil effects, boosting antioxidant enzyme activity, and facilitating nitrogen uptake, photosynthesis, and water use efficiency.
June 2025 in “Current Trends in Biotechnology and Pharmacy” This study found that when applied for 24 hours, a polyherbal formulation made from Ficus religiosa and Abrus precatorious promoted more significant hair growth in Male Wistar rats than Minoxidil and the control group, and the extracts also exhibited notable antibacterial activities.
August 2024 in “Siberian Journal of Life Sciences and Agriculture” In this study, researchers found that both oral and percutaneous applications of melatonin and lyotritone in laboratory rats enhanced hair quality and growth rate compared to a control group, which showed slower hair growth and lower hair quality.
This review highlights various plant-based and herbal treatments that reportedly help prevent hair loss and encourage hair growth. It also explores the molecular mechanisms, identified plant compounds, recent technologies such as nanoarchitectonics, and patents related to hair growth promotion.
In this study, deer hair follicles were shown to be an effective in vitro bioassay model, demonstrating that K(ATP) channel modulators directly influence hair follicle growth through specific channel types.
January 2020 in “International Journal of Herbal Medicine” This study concluded that freeze-dried and natural forms of a hair growth promoter derived from traditional recipes have mostly similar chemical constituents.
2 citations
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February 2024 in “Toxins” This study found that bee venom accelerated the transition from the telogen to anagen phase in mice, increasing hair growth by day 14, and suggested that bee venom may enhance adipose-derived stem cell activity by upregulating growth factor secretion.
October 2022 in “Regenerative Biomaterials” This study demonstrated that fibrin hydrogels support skin-derived precursors in hair follicle neogenesis in mice, with new hair growth and regeneration of blood vessels and sebaceous glands observed.
34 citations
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January 2022 in “Molecules/Molecules online/Molecules annual” This review highlights the use of natural products in cosmetic-containing herbals for skin and hair care but reports no new clinical results, calling attention to their claimed curative properties and minimal side effects.
5 citations
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September 2024 in “Life” Natural products can safely and effectively treat various human diseases.
January 2024 in “Elsevier eBooks” In this chapter, the authors discuss various plant biomass sources, such as Aloe vera and cocoa, highlighting their potential benefits in cosmetics for addressing skin and hair issues like aging, inflammation, and dandruff.
35 citations
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March 2005 in “Journal of Investigative Dermatology” In this in vitro study, minoxidil, diazoxide, and the novel compound NNC 55-0118 increased hair follicle growth, supporting deer follicles as a viable bioassay for ATP-sensitive potassium channel modulators.