Novel and Established Potassium Channel Openers Stimulate Hair Growth in Vitro: Modes of Action in Hair Follicles

January 2005

Gareth Davies, M. Julie Thornton, Tracey J. Jenner, Yi‐Ju Chen, John Bondo Hansen, Richard D. Carr, Valerie A. Randall

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ATP-sensitive potassium channel openers minoxidil diazoxide NNC 55-0118 tolbutamide glibenclamide SUR 1 receptors SUR 2 receptors Rogaine

Studysummary In this study, deer hair follicles were shown to be an effective in vitro bioassay model, demonstrating that K(ATP) channel modulators directly influence hair follicle growth through specific channel types.

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