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In this study, a self-adaptive nanozyme embedded in a madecassoside-enriched hydrogel demonstrated strong antibacterial efficacy and accelerated healing in wounds infected with drug-resistant bacteria, as evidenced by improved repair and regeneration in MRSA-infected mice and preclinical pig models.

This study found that keratin biomaterials derived from human hair promoted significant motor function recovery and neuromuscular regeneration in animal models of peripheral nerve injuries.

In this study, researchers developed a method to create skin organoids using spinning bioreactors, facilitating efficient high-throughput drug screening, and found that Minoxidil activates the Wnt/beta-catenin signaling pathway in these models.

This study highlights that a novel radially aligned nanofiber scaffold with dual growth factor gradients significantly enhances wound healing, promoting cell migration, epidermal regeneration, and angiogenesis, ultimately leading to improved wound closure, immune regulation, and tissue remodeling compared to other groups.

This study found that the RADA-GHK and RADA-KGHK peptide hydrogels improved wound healing and cell growth without cytotoxicity, suggesting potential for use in skin regeneration.

This review discusses the biological properties and potential applications of PCL and barium titanate composites in biomedical fields and reports no new experimental findings; the authors highlight the need for further research.

This study demonstrated that gene-corrected 3D skin constructs from RDEB patient-derived iPSCs, grafted onto immunocompetent mice, showed normal collagen VII expression after two months.

This review classifies engineered nanomaterials by composition and application in biomedicine, highlighting diverse uses like regenerative medicine and potential occupational side effects, but reports no new clinical results.

This study found that echogenic liposomes improved the delivery and penetration of CRISPR/Cas9 genetic materials into cardiomyocytes, both in vitro and in vivo, especially when combined with ultrasound, highlighting a promising strategy for cardiovascular gene therapy.

This study found that using insulin-like growth factor 1 with bone marrow-derived mesenchymal stem cells in a collagen-chitosan scaffold enhanced wound healing and hair follicle regeneration in rats.

This study found that soy-based nanofibrous scaffolds enhanced wound closure and tissue regeneration via the ER-β pathways in both mouse and human skin, suggesting a potential for effective wound healing applications.

This review discusses the role of organoids and organ chips in advancing ophthalmological research and therapeutic evaluation, but it reports no new clinical findings.

This review discusses the mechanisms and potential therapeutic benefits of mesenchymal stromal cell-derived extracellular vesicles delivered via biomaterials, but reports no new clinical results.

This study introduces a customizable 3D-printed microscope stage insert for inverted confocal microscopes, improving accessibility and usability of intravital microscopy for observing cell dynamics in live mice.

This review discusses the development and clinical progression of PROTAC technology for targeted protein degradation, highlighting its potential to address previously "undruggable" targets but reports no new clinical results.

In an animal study with a skin defect model, this research reported that curcumin-loaded hydrogels made from recombinant humanized collagen and an eco-friendly crosslinker enhanced wound repair by promoting angiogenesis, granulation tissue formation, and hair follicle neogenesis, while providing antioxidant benefits.

This review discusses recent advances in scarless wound healing research, focusing on the roles of mechanobiology and immunology, and reports no new clinical results; the authors highlight the potential of next-generation human skin equivalents in understanding these mechanisms.

This study observed that DMAP scaffolds in a full-thickness wound model promote dermal appendage regeneration by activating humoral immunity, specifically through B cell activation and antibody production, even when adaptive immune cells' infiltration is restricted.

In this study, researchers developed an in vitro airway-organoid model using human lung-derived cell lines on RADA16-I hydrogels to serve as a potential tool for studying adenovirus isolation, pathogenesis, and antiviral drug screening.

This study achieved regeneration of hair follicle-like structures and erector muscle of hair in vitro by simulating cellular organization and applying mechanical stimuli.

In this study, researchers developed injectable micropore-forming hydrogels that enhance tissue adhesion strength and promote wound healing by allowing better cell infiltration and inducing hair follicle regeneration in skin incision wound models.

This abstract outlines the historical development and medical validation of artificial hair implants, particularly the approval and improvement of the Biofibre® implant technique in Europe and Australia, and highlights its advantages as the latest advancement in hair restoration treatments.

This study found that combining polybrene and a ROCK inhibitor can effectively expand human keratinocyte stem/progenitor cells carrying a transgene, aiding their use in regenerative medicine.

This study presents a new wireless bioelectronic system powered by ambient Wi-Fi signals that enhances wound healing by providing electrical stimulation and real-time monitoring, offering a promising solution for at-home treatment and regenerative therapy.

This study provides a comprehensive review of the use of electrospinning technology to create 3D porous structures for bone implants, emphasizing the synergy between biomedicine and materials science necessary for developing orthopedic materials.

This study found that recombinant human hair keratin proteins K31 and K81 show greater potential for inducing skin cell differentiation compared to natural keratin coatings.

This study found that island grafting in guinea pigs enabled the isolated study of early skin regeneration processes, distinguishing them from natural wound closure mechanisms like epithelialization and contraction.

This review highlights how integrating medicinal chemistry with delivery science could transform the limitations of PROTACs—such as poor solubility and low cell permeability—into strengths, potentially advancing these compounds from experimental stages to clinical applications by optimizing their delivery and enhancing therapeutic efficacy.

Advancements in biomaterials and nanotechnology are improving medical applications like hair growth, bone regeneration, and cancer treatment.