This study found that two formulations of finasteride tablets are bioequivalent in healthy male volunteers, with similar pharmacokinetic profiles.
August 2023 in “MPPKI (Media Publikasi Promosi Kesehatan Indonesia) : The Indonesia journal of health promotion” In this study, researchers used a UV-Vis Spectrophotometer to qualitatively and quantitatively analyze Dutasteride residues in human plasma, achieving a total recovery rate of 64.992%, and determined that the BTB reagent effectively selected compounds not analyzed in their research.
12 citations
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November 2014 in “Bioscience, Biotechnology, and Biochemistry” In this study, the researchers successfully increased dipicolinic acid production in Bacillus subtilis by genetically modifying the spoVF operon, achieving a significant productivity improvement in the culture medium.
October 2023 in “International Journal of Cosmetic Science” In this study, researchers developed WS Biotin, a new water-soluble form of biotin, and found that it significantly improves water solubility compared to free biotin and enhances hair-related keratin expression, gene activity for hair growth in vitro, while also reducing melanin content in skin cells.
June 2026 in “Scholarly review .” This review discusses the impact of endocrine-disrupting chemicals on pediatric health, linking them to various disorders, and calls for improved biomonitoring strategies and precautionary policies.
127 citations
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June 2008 in “British Journal of Clinical Pharmacology” This study supports the conclusion that the hormetic dose-response model is the most prevalent and fundamental model in biological and biomedical sciences, applicable to a wide range of clinical conditions.
1 citations
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January 1997 in “Proceedings of the British Society of Animal Science” This review addresses the role of biotin in animal metabolism, emphasizing the need for further research to understand its dietary and microbial sources in different developmental stages in pre-ruminant and mature ruminant animals, without reporting new experimental results.
23 citations
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January 1991 in “Journal of Animal Science” In this study, dietary biotin supplementation showed no significant benefit on reproductive performance in sows or pre-weaning growth and mortality in piglets.
This study found that Finasteride Dispersible Tablets, prepared with an optimized prescription, disintegrate quickly, disperse well, and have a high dissolution speed, suitable for industrial production.
11 citations
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December 2010 in “Journal of Inclusion Phenomena and Macrocyclic Chemistry” This study found that forming solid dispersions and inclusion complexes of finasteride significantly increased its solubility compared to its pure form.
5 citations
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October 2019 in “Giornale italiano di dermatologia e venereologia” This review highlights the potential benefits of biotin in treating skin disorders related to biotin deficiency but reports no new clinical results.
26 citations
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December 2012 in “Bioanalysis” The researchers reported that glucuronides stored as dried blood spots under ambient conditions exhibited stability equivalent to liquid samples stored at -80°C.
August 2022 in “Journal of the American Academy of Dermatology” This review discusses the risk factors, clinical presentation, diagnosis, and management of dermatoses linked to B-complex vitamin deficiencies, including biotin, but does not address risks from over-supplementation.
This review highlights the potential analytic interference of high-dose biotin with immunochemical tests, which may lead to diagnostic errors and suggests pausing biotin consumption before laboratory testing.
1 citations
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April 2015 in “The FASEB journal” In this study using SKH-1 mice, researchers observed that acute UVB exposure increased expression of retinoid metabolism proteins and decreased retinol storage enzyme levels, suggesting enhanced retinoic acid synthesis in the epidermis.
30 citations
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July 1984 in “Journal of Animal Science” In this study, sows fed a diet with added biotin weaned more pigs per litter overall, though other reproductive and health metrics showed no improvement.
January 2005 in “Journal of Elinical Research” This study found that the pharmacokinetic profile of finasteride capsules and tablets in healthy volunteers is bioequivalent.
74 citations
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July 1979 in “Lancet” This case report describes a 10-month-old boy with dermatitis, alopecia, and hypotonia who showed dramatic improvement with oral biotin, suggesting a possible defect in biotin absorption or transport.
44 citations
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April 2003 in “European journal of pharmaceutical sciences” This study found that targeting the hair follicle can be increased by using lipophilic drugs combined with surfactant solutions and propylene glycol.
184 citations
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August 1983 in “The journal of pediatrics/The Journal of pediatrics” In this study, biotinidase deficiency in children usually presented with neurological or skin symptoms, while metabolic ketoacidosis and organic aciduria appeared later.
156 citations
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August 2014 in “Cochrane library” This study suggests that oral budesonide may not effectively maintain remission in Crohn's disease beyond three months, with minor benefits that are outweighed by increased rates of treatment-related adverse events.
53 citations
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March 2003 in “Journal of Investigative Dermatology” This study found that human keratinocytes express a sodium-dependent multivitamin transporter for biotin, pantothenic acid, and lipoic acid, including a highly specific biotin transport component.
November 2010 in “Value in Health” Real-life dosing of biologics for plaque psoriasis often deviates from recommended guidelines, especially for high-need patients.
11 citations
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July 2023 in “Applied Nanoscience” January 2004 in “Chinese Journal of Pharmaceuticals” This study concluded that the test and reference finasteride tablets were bioequivalent in terms of pharmacokinetic parameters in healthy male volunteers.
4 citations
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January 2011 in “Chinese Herbal Medicines” This study found that improving the solubility of wogonin can significantly enhance its bioavailability in Beagle dogs.
5 citations
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December 1942 in “Journal of the American Medical Association” This article reviews the classification and characteristics of water soluble vitamins, focusing on their varying solubility and functions, and reports no new experimental findings.
57 citations
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February 2018 in “Journal of the American Academy of Dermatology” This review critiques the unwarranted promotion of biotin for hair and nail improvements, noting the lack of evidence for routine use and highlighting concerning trends in consumer and physician practices.
14 citations
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February 2011 in “Drug Metabolism and Disposition” This study examined the pharmacokinetics of finasteride in pigs and found that ketoconazole coadministration affected its distribution across various plasma compartments, bile, and urine.
May 2024 in “Physiologia Plantarum” In this study, Bacillus subtilis strain ALC_02 was observed to enhance phosphorus acquisition in phosphorus-limited dwarf tomato plants by promoting root and root hair growth, with potential implications for developing effective bacterial P biofertilizers.