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This study found that while biotin treatment improves clinical and biochemical symptoms in patients with biotinidase deficiency, some experience lasting neurological damage, and it is uncertain if early treatment can prevent this.

This study found that 38% of women with hair loss had a biotin deficiency, suggesting oral biotin supplementation should be based on confirmed biotin deficiency rather than as a general treatment.

This study concluded that combining vertical and transverse sections of scalp biopsy specimens improves diagnostic yield for certain hair disorders without increasing costs.

This review provides an overview of current research on AD-MSCs, PRP, and biomaterials, highlighting their safety and efficacy in treating soft tissue defects and chronic wounds without major side effects.

This study found that hair thickness and density increased after treatment with human follicle mesenchymal stem cells and platelet rich plasma, associated with enhanced Wnt signaling and platelet derived growth factors.

In this study, researchers found that electrospun membranes with aligned surface topography advanced the immune response towards an adaptive stage and highlighted the role of T cells in hair follicle regeneration in mice, showcasing the intricate interactions between immune and skin cells.

This study demonstrated that bioengineered hair follicles reconstituted from embryonic skin cells and transplanted into hosts can restore physiological hair functions, suggesting potential applications for treating alopecia.

This study developed an in vitro model revealing that hair follicle spheroids enhanced both sweat gland and hair follicle differentiation within bioprinted scaffolds, while microenvironmental cues supported persistent regeneration.

This study found that both Th1 and Th2 immune responses, along with IL-23 and IL-32 cytokine pathways, are active in alopecia areata lesions, and corticosteroid injections significantly altered these immune markers.

This study found that the multifunctional FEA-PCEI dressing significantly accelerated wound healing, reduced scar formation, and promoted hair follicle neogenesis while providing antibacterial and anti-inflammatory benefits.

This study developed thermo-reversible glycol chitosan hydrogels that effectively form and maintain 3D cell spheroids within one day, offering a simplified method for creating biologically realistic cultures for tissue regeneration and drug screening applications.

This study observed that skin pigmentation significantly attenuates bioluminescent signals in C57Bl/6 mice, complicating quantitative optical imaging and requiring consideration in experimental design.

This study found that nanofibrous membranes containing PNA nanogels enhanced wound healing in mice by modulating reactive oxygen species levels, improving cell adhesion and proliferation.

This review discusses advances in skin tissue engineering, focusing on scaffold-free approaches and the application of stem cells, and reports no new research findings.

This study found that methanol extract from Anisomeles indica has significant antidepressant and antidiarrheal effects in animal models and notable anti-inflammatory activity in vitro.

This review critiques the unwarranted promotion of biotin for hair and nail improvements, noting the lack of evidence for routine use and highlighting concerning trends in consumer and physician practices.

This article reviews methods to enhance epithelial–mesenchymal interactions for hair follicle bioengineering but does not present new experimental results; it emphasizes optimizing combinations for successful regeneration.

This study found that oral biotin supplementation improved outcomes in a mouse model of inflammatory bowel disease by reducing inflammatory cytokine production and enhancing intestinal barrier integrity, suggesting potential therapeutic benefits for IBD patients.

This review discusses two genetic disorders affecting biotin metabolism, each resulting in distinctive skin and hair manifestations, and outlines the associated serious metabolic complications.

This case study of three siblings highlights the importance of recognizing dermatologic signs—alopecia and periorificial dermatitis—for early diagnosis and treatment of biotin-responsive multiple carboxylase deficiency.

This review discusses the importance of omega-3 fatty acids for human health and explores recent advancements in genetically modifying plants to produce these essential nutrients, but reports no new results.

This study observed that hepatocyte adhesion to human hair keratin biomaterials was mediated by the hepatic ASGPR, as blocking this receptor reduced cell attachment.

This study found that human keratinocytes express a sodium-dependent multivitamin transporter for biotin, pantothenic acid, and lipoic acid, including a highly specific biotin transport component.

This study reports a method for efficiently synthesizing chromeno-pyrimidine-N-oxides in good to excellent yields, confirmed by X-ray analysis, through a reaction between 4-chloro-3-formylcoumarin and aromatic carboximide oximes.

This study found that hyperandrogenemia in Chinese women with PCOS is associated with higher risks of type 2 diabetes and obesity, suggesting it should be prioritized in managing PCOS-related infertility.

This review discusses the biology of antiandrogens and highlights available bioassay models to predict their therapeutic effects on human skin, reporting no new clinical results.

This study suggests that a sandwich-structured wound dressing with bioceramic and polylactic acid layers may improve burn wound healing by absorbing exudates and promoting hair follicle regeneration.

This review focuses on S100A6, a Ca²⁺-binding protein, detailing its role in cell functions, the regulation of its expression, and its potential as a biomarker and therapeutic target in various diseases.

This study reported successful treatment of biotin deficiency in three patients receiving total parenteral nutrition, suggesting current biotin supplementation recommendations may be inadequate to maintain normal biotin status.