Alopecia and Periorificial Dermatitis in Biotin-Responsive Multiple Carboxylase Deficiency
July 1983
in “
Journal of the American Academy of Dermatology
”
TLDR Biotin supplements can effectively treat hair loss and skin issues in certain enzyme deficiencies.
The document discussed a case of biotin-responsive multiple carboxylase deficiency, which was associated with symptoms of alopecia and periorificial dermatitis. This condition was characterized by a deficiency in multiple carboxylase enzymes, which are crucial for various metabolic processes. The study highlighted that biotin supplementation effectively alleviated the symptoms, indicating the importance of biotin in managing this deficiency. The findings underscored the potential for biotin therapy in treating similar cases of alopecia and dermatitis linked to enzyme deficiencies.