21 citations
,
September 2011 in “Journal of Pharmaceutical Sciences” This study found that the desolvation of finasteride hydrate solvates is highly dependent on the physical environment, complicating investigations but providing insight through complementary analysis techniques.
21 citations
,
May 1996 in “Current problems in dermatology” This article reviews various causes and investigative techniques for different forms of alopecia and reports no new findings.
20 citations
,
March 2020 in “International Journal of Biological Macromolecules” Lower acetylation makes chitin nanofibers thinner and more suitable for various uses.
20 citations
,
November 2019 in “Biomolecules” This study found that finasteride impaired stress reactivity and reduced exploratory and impulsive behaviors in rats, potentially by altering the hypothalamus-pituitary-adrenal axis function.
20 citations
,
October 2018 in “Clinical Drug Investigation” This study observed that men receiving dutasteride for benign prostatic hyperplasia did not show significant differences in neuropsychological assessments compared to a control group not on dutasteride.
20 citations
,
June 2014 in “BMC genomics” This study identified the placenta at the base of the ovary as the origin of poplar seed hair development and detailed transcriptome dynamics during the growth process.
20 citations
,
July 1988 in “Clinics in dermatology” This article reviews the current practices and interpretations of research data on permanent waving and hair straightening, but does not present any new research findings.
19 citations
,
May 1984 in “Digestive diseases and sciences” A young woman's Cronkhite-Canada syndrome improved on its own after she gave birth.
18 citations
,
May 2013 in “Cutaneous and Ocular Toxicology” This study suggests that cutaneous adverse reactions to bortezomib and lenalidomide are more frequent than reported, impacting patients' quality of life and may require dermatological consultation for proper management.
18 citations
,
February 2010 in “Odontology” This report describes Rabson-Mendenhall syndrome cases in two siblings and briefly reviews the literature, highlighting insulin receptor gene mutations as the underlying cause.
18 citations
,
January 2008 in “Sen'i Gakkaishi” This study observed that repeated perm treatments decrease disulfide bonds in hair due to their conversion largely into cysteic acid, affecting the waving efficiency depending on the reduction agent used.
17 citations
,
July 2019 in “Scientific reports” This study investigated lipid loss in hair caused by surfactants and found that surface and internal modifications can significantly protect different lipids from depletion, with internal modification preventing 52.0 to 81.3% of lipids in certain groups.
17 citations
,
August 2018 in “BMC Genomics” The researchers found that HOXC13 regulates different keratin proteins in a mixed manner, with certain SNPs impeding this regulation, while also demonstrating negative-feedback by HOXC13 and positive regulation by LEF1 and melatonin on the HOXC13 promoter.
17 citations
,
September 2017 in “Journal of Cosmetic Dermatology” In this study of women with PCOS, hirsutism strongly correlated with metabolic abnormalities, while acne and androgenic alopecia were not clear markers of biochemical hyperandrogenemia or metabolic dysfunction.
17 citations
,
May 2015 in “Nanomedicine: Nanotechnology, Biology and Medicine” This study found that lipid nanocarriers called squarticles, conjugated with an antibody, enhanced minoxidil uptake in dermal papilla cells, potentially improving alopecia treatments.
17 citations
,
September 2014 in “PLoS ONE” This study found that SK2 channels in sensory terminals of rat muscle spindles and hair follicles may play a crucial role in modulating mechanosensory transduction by influencing receptor potentials through Ca2+-activated K+ currents.
17 citations
,
May 2010 in “Journal of Dermatological Science” This study found that erythropoietin promotes hair growth by stimulating dermal papilla cells with functional erythropoietin receptors, enhancing hair shaft elongation and anagen phase in cultured human hair follicles and in mice.
16 citations
,
September 2018 in “Scientific reports” This study demonstrates that keratinocyte cell lines derived from cultured hair follicles can fully differentiate in organotypic skin models, offering a minimally invasive alternative to obtaining keratinocytes for research.
16 citations
,
August 2004 in “Tetrahedron” In this study, all stereoisomers of cyoctol were synthesized and tested, revealing that contrary to initial patent claims, cyoctol does not function as an anti-androgen.
14 citations
,
July 2021 in “Biomedicines” This review discusses the roles of platelets in hemostasis and wound repair, the preparation methods for platelet concentrates, and their therapeutic applications in medicine and dentistry, reporting no new clinical results.
14 citations
,
January 2021 in “Scientific Reports” This study found that "micro skin tissue columns" improved wound healing by enhancing re-epithelialization, collagen deposition, dermal remodeling, and reducing inflammation without causing long-term donor site morbidity.
14 citations
,
January 2018 in “Advances in Clinical Chemistry” This review discusses the evaluation of hyperandrogenemia in women and hypogonadism in men across different life stages and presents biomarkers used for diagnosing male hypogonadism, reporting no new clinical results.
13 citations
,
May 2021 in “Plants” This study found that the n-hexane fraction from Leea indica leaves significantly increased hair growth in mice and showed potential as a natural treatment for alopecia.
13 citations
,
October 2017 in “Bioorganic & Medicinal Chemistry” This study found that compound 3, a tetrahydropyridoindole carboxymethylated at position 5, significantly inhibited sorbitol accumulation in both rat eye lenses and tissues affected by diabetes, indicating its potential as a lead compound for ALR2 inhibition.
13 citations
,
October 2010 in “Pharmacogenomics” This study constructed a panel of pharmacokinetic and pharmacodynamic genes, revealing that current SNP chips insufficiently capture many drug-response gene variants, highlighting the need for complementary genetic approaches.
13 citations
,
October 2002 in “Journal of Biochemical and Biophysical Methods” This study found that men with androgenic alopecia had significantly higher levels of certain urinary steroid metabolites, suggesting increased 5 alpha-reductase activity and possible mild hyperadrenal activity.
12 citations
,
March 2019 in “Lasers in Surgery and Medicine” This study found that low-level laser therapy increased the expression of proteins in dermal papilla tissues, suggesting it promotes hair growth in male androgenetic alopecia patients.
12 citations
,
December 2017 in “Scientific reports” This study reported that pulverizing hair samples significantly improves the precision of testosterone measurement, with higher testosterone concentrations observed in men than in women.
12 citations
,
January 2010 in “Pediatric Health” This review discusses treatment strategies for PCOS, focusing on using insulin-sensitizing medications alongside weight reduction and exercise to improve hyperinsulinemia and hyperandrogenism, and reports no new results.
12 citations
,
February 1998 in “Gene” This study identified two high sulfur protein genes, B2E and B2F, in rats, which are expressed in hair cortical cells during anagen and contribute to hair fiber production.