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This review discusses the potential role of Wnt signaling in aging-related heart diseases and reports no clinical results.

This study found that finasteride decreased plasma dihydrotestosterone levels and altered steroid metabolism, similar to the profile of male pseudohermaphrodites with inherited 5a-reductase deficiency.

In this review, the researchers detailed how the p63 transcription factor influences epithelial stem cell activities such as self-renewal, differentiation, and proliferation, highlighting the role of TAp63 and ΔNp63 isoforms in both normal tissue development and cancer pathogenesis.

This study found that acute finasteride treatment decreased ethanol intake in male C57BL/6J mice, whereas chronic treatment showed diminished effects, implying compensatory changes in neurosteroid modulation.

This review discusses the role of CYP gene polymorphisms in exacerbating hyperandrogenism in women with PCOS and reports no clinical results; further validation of this hypothesis is needed.

This review offers evidence-based recommendations for diagnosing and treating female pattern hair loss, emphasizing clinical assessment and starting treatment with minoxidil, while noting that measurement of certain hormones and vitamins is optional.

This study found that age, pre-pregnancy BMI, and family history of diabetes were independent predictors of gestational diabetes in Iranian women, with selective screening missing few cases among low-risk groups.

This study found that combining cyproterone acetate with testosterone enanthate was highly effective in suppressing spermatogenesis, suggesting potential as a reversible male contraceptive method.

In this study, ketoconazole treatment improved acne in all women and reduced hirsutism in some, but it caused several side effects and requires careful monitoring.

This genome-wide association study identified 20 genetic signals at 15 risk loci related to severe acne, revealing new insights into its genetic predisposition, particularly affecting skin structure and maintenance.

This review discusses the integration of drug repurposing with personalized medicine through off-label prescribing and reports no new results, highlighting the potential for systematic exploration using omics technologies.

This study suggests that age-related changes in skin elasticity reduce its stability against wrinkling, and anti-aging strategies should focus on addressing elastic mismatches between skin layers.

This study demonstrated that engineered skin substitutes using human keratinocytes and murine dermal papilla cells can develop pigmented hairs without sebaceous glands, suggesting separate pathways for hair development and eruption.

This review discusses recent research and applications of RADA16 and RADA16-based peptide scaffolds in biomedicine, including their roles in tissue repair and drug delivery, but reports no new clinical results.

In this study, a novel electrochemical sensor using a molecularly imprinted polymer was developed for the sensitive detection of minoxidil, successfully measuring its concentration in real samples.

In this study using a mouse model and human hair follicle cells, shikimic acid was found to promote hair growth and may serve as a new therapeutic agent for alopecia.

In this study, epidermal Notch activation increased jagged 1 expression, leading to skin changes like thickening and blistering, with these effects inhibited when jagged 1 was absent.

This study found that the moisture content of human hair significantly influences the type of fracture under tensile loading, with low or high humidity levels leading to smooth fractures and intermediate humidity resulting in step fractures.

This study found a significant shift to the telogen phase in the hair growth of children with classical marasmus compared to normal children, suggesting a connection to the chronicity of the condition.

This study found that in squamous cell carcinomas, the inhibition of the tumor-suppressor function of TAp73β by ΔNp63α occurs through promoter squelching, not direct protein interaction.

This study used bioinformatics to explore molecular differences in testicular and ovarian responses to SARS-CoV-2, identifying genes that could be associated with sex differences in infection outcomes.

This study found that macrophage-stimulating protein (MSP) enhanced hair growth in both human hair follicles cultured in vitro and in mice through the promotion of anagen phase induction.

In this study, Polygonum multiflorum Radix promoted hair growth in mice, with oral administration being more effective, likely through FGF-7, while topical application favored SHH-related mechanisms.

This study found that Transcutol P significantly enhanced the skin penetration of Finasteride in vitro, while cationic and anionic surfactants did not show such effects.

This study found that keratin coatings from human hair may improve the colony-forming efficiency of human mesenchymal stem cells by moderating donor variability, suggesting a potential use in clinical applications.

This review examines the benefits and potential risks of androgen replacement therapy for male hypogonadism but reports no new clinical results; the authors highlight the need for careful risk assessment, especially in older men.

This article reviews the biological causes and treatment options for facial aging but reports no new clinical findings.

Human hair follicles have a unique metabolism that changes between growth stages and may contribute to baldness.

This review discusses the etiology, diagnosis, and management strategies for hirsutism, noting that serious underlying disorders are rare and emphasizing targeted treatment to manage testosterone's effects.

This study found that topical cilostazol promotes hair growth, enhances hair follicle activities, and may serve as a potential treatment for alopecia.