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Changes in genes FGA, VWF, and ACTG1 may contribute to pemphigus vulgaris.

This study found that alkylation of kerateine cysteine residues created a cell-compatible method for controlling hydrogel erosion rates and therapeutic agent release in keratin-based systems.

This study found that dual 5α-reductase inhibitors in rats decreased sperm quality and led to reduced pregnancy success, suggesting potential for use in male contraception.

This review discusses current clinical trials targeting Wnt signaling in gastrointestinal cancers and reports no new results; the authors highlight challenges and consider alternative strategies for cancer treatment.

This study reports that TFM-4AS-1, a selective androgen receptor modulator, promoted bone and muscle growth with reduced effects on reproductive organs in ovariectomized rats.

This review explores current strategies to enhance extracellular vesicle-based delivery of CRISPR/Cas systems, addressing efficiency challenges and suggesting future directions to bridge gene editing technologies with clinical applications.

This review explores the complex relationships between ferroptosis, anastasis, and chemoresistance in cancer therapy, highlighting the potential of combining ferroptosis with immunotherapy to overcome resistance and improve personalized cancer treatments.

This review highlights the potential of Asteraceae plants as antidiabetic agents and their beneficial effects on conditions such as cardiovascular disease and liver cirrhosis, suggesting their use as food and nutraceuticals could help manage diabetes.

This review summarizes the role of non-coding RNAs in hair follicle regeneration and highlights potential therapeutic strategies, though it reports no new experimental results.

This review highlights cepharanthine as a promising candidate for COVID-19 treatment due to its antiviral activity against SARS-CoV-2 and favorable pharmacokinetic and safety profile, but reports no new clinical results.

This study reports differential gene expression in the leading edge and inner surface epithelial cells of murine eyelids, suggesting that distinct signaling pathways are active during embryonic eyelid closure.

This review discusses various treatment options for non-classic congenital adrenal hyperplasia due to 21α-hydroxylase and 11β-hydroxylase deficiencies without providing new clinical results.

This review explores molecular targets for head and neck squamous cell carcinoma and discusses potential advancements in radiopharmaceuticals for targeted radionuclide therapy, reporting no new clinical results.

In this study, the researchers performed a comparative analysis of drug-target interaction data from multiple databases to refine drug repurposing strategies, revealing potential associations between drug characteristics and therapeutic groups, and predicting repositioning opportunities for FDA-approved drugs across major cancer types.

This review highlights the potential of ellagic acid for treating various skin conditions due to its antioxidant, anti-inflammatory, and depigmenting properties, but notes that novel formulations are needed to overcome its poor solubility and skin permeability to enhance clinical efficacy.

This narrative review emphasizes the significant improvements in mental well-being linked to gender-affirming treatments while highlighting the need for ongoing research into hormone therapy's long-term effects and its impact on transgender individuals' reproductive health.

In this study, researchers used computational modeling and virtual screening to identify two FDA-approved drugs, Tadalafil and Finasteride, that may effectively inhibit key proteins involved in melanoma progression, suggesting potential for new therapeutic strategies against aggressive melanoma.

This study developed a validated gas chromatography–tandem mass spectrometry assay to assess sex steroid hormones in cerebrospinal fluid, finding substantial levels of DHEA, androstenedione, and testosterone, with strong correlations to serum levels, providing insight into sex steroid dynamics in the human CNS.

In this review, several studies on Astragalus species, particularly Astragalus membranaceus, highlight their skin rejuvenating, photoprotective, antimicrobial, and wound-healing properties, though the authors note limitations due to reliance on non-human studies and short trial durations.

This study suggests that Staphylococcus capitis ferment filtrate (SCFF) may promote hair growth and scalp health by modulating pathways related to hair loss, aging, and oxidative stress in vitro.

This study reported that Gunja (Abrus precatorius Linn.) demonstrates various pharmacological activities, including antifertility, hair growth promotion, immunomodulatory effects, and anticancer properties, supported by its phytochemical composition and analytical advancements, suggesting its potential in Ayurvedic therapeutic applications and future drug development.

This review discusses the potential benefits of hyperthermia in cancer therapy, combined with natural compounds, to enhance treatment efficacy and reports no new clinical results.

This review highlights brimonidine’s potential as a dermatological agent, noting its ability to improve rosacea-related facial redness and its effectiveness in various other skin conditions due to its vasoconstrictive and anti-inflammatory actions, with minimal systemic absorption and a favorable safety profile for long-term use.

In this study, oral administration of ginsenoside Rf from Panax ginseng promoted hair regrowth and increased hair thickness in a mouse model of androgenetic alopecia by enhancing androgen receptor degradation, highlighting its potential for cosmetic and functional food applications.

This review highlights hypochlorous acid's potential benefits in various medical fields due to its antimicrobial and healing properties but stresses the need for further research on dosing and product development.

The researchers reported that PPARβ/δ may influence the yak hair follicle cycle by modulating lipid metabolism in dermal papilla cells, with varying expression during different hair growth phases, affecting both lipid content and cell proliferation.

This article reviews recent advancements in forensic hair testing, emphasizing its growing use for detecting past substance exposure, identifying emerging trends like micro-segmentation and hair scanning, and proposing standardized procedures to improve reliability and application in forensic toxicology.

This review examines synthetic derivatives of curcumin for treating diabetes and cancer, reporting potential pharmacokinetic improvements and enhanced biological activity, but highlights ongoing challenges with bioavailability and stability, as well as gaps in translational research.

This study investigated improving Finasteride's water solubility using trimethyl-β-cyclodextrin (TM-β-CD) and β-cyclodextrin (β-CD) as carriers, finding that β-CD improved Fin's cumulative release, while TM-β-CD enhanced its solubility, with computational data supporting these outcomes.