April 2023 in “International journal of molecular sciences” This study found that scalp disorders, such as hair loss and itching, can be associated with collagen VI mutations, thus highlighting the need to investigate scalp involvement in these patients.
March 2014 in “Journal of The American Academy of Dermatology” TNF-a may not be as involved in certain types of hair loss as previously thought.
44 citations
,
February 2015 in “Journal of the American Academy of Dermatology” This study found that combination therapy with diphenylcyclopropenone and anthralin was more effective for complete hair regrowth in chronic extensive alopecia areata than diphenylcyclopropenone alone, despite more common side effects.
1 citations
,
June 2021 in “International Journal of Dermatology” This study found that patients with alopecia areata had significantly lower serum vitamin D levels compared to controls, but these levels did not impact disease severity or pattern.
157 citations
,
August 2010 in “Lupus” This review discusses the various common, rare, and unusual skin manifestations of lupus erythematosus and highlights the importance of accurate diagnosis, but it reports no new clinical results.
72 citations
,
April 2008 in “Organogenesis” This review discusses the roles of Wnt signaling in skin organogenesis and related processes but reports no new experimental results, highlighting areas for future research.
66 citations
,
January 2001 in “Vitamins and hormones” This chapter reviews the role of androgen receptors in mediating the actions of androgens in specific tissues and provides no new experimental findings.
59 citations
,
June 2008 in “Journal of The American Academy of Dermatology” This article reviews major types of genetic hair shaft defects and associated syndromes, emphasizing understanding histologic features and diagnostic methods, but reports no new clinical findings.
58 citations
,
January 2018 in “International Journal of Women's Dermatology” This review discusses the psychological impact of alopecia on women and reports no new clinical findings, highlighting the effect on self-esteem and quality of life.
56 citations
,
February 2006 in “American journal of physiology. Cell physiology” This study observed that in hormone-starved prostate cancer cells, the androgen 5alpha-dihydrotestosterone rapidly induces matriptase activation and shedding, which involves androgen receptor signaling and requires both transcription and protein synthesis.
54 citations
,
March 1987 in “Journal of The American Academy of Dermatology” In this study, 3% topical minoxidil showed some efficacy in hair regrowth for patients with extensive alopecia areata, especially those with less than total scalp hair loss, but did not lead to complete remission.
39 citations
,
October 2010 in “Journal of The American Academy of Dermatology” This study reported that alopecia occurred in 2.5% of patients with mycosis fungoides or Sézary syndrome, with some cases resembling alopecia areata and others associated with specific skin lesions.
30 citations
,
November 2013 in “PLOS ONE” This study found that androgen/androgen receptor signaling accelerates premature senescence in dermal papilla cells, highlighting a potential target for treating androgenetic alopecia.
17 citations
,
June 2016 in “Croatian Medical Journal” In this study, vitiligo and alopecia areata were more common among patients with chronic graft-vs-host disease than previously reported, linked to higher NIH skin scores and greater immunosuppressive treatment.
12 citations
,
January 1984 in “Clinics in Dermatology” This article discusses the decline in recognition and appropriate testing of syphilis by medical students due to limited clinical exposure and inconsistent education, with no new clinical results reported.
2 citations
,
January 2015 in “Springer eBooks” Early diagnosis and aggressive treatment are crucial for Cicatricial Alopecia, and treatment effectiveness varies among patients.
December 2025 in “GeroScience” This study found that both genetic and epigenetic factors significantly influence age-related facial skin aging, with lifestyle and environmental factors also playing a substantial role.
April 2016 in “Journal of the American Academy of Dermatology” This study found that in a tertiary academic institution, nearly 1 in 5 dermatology consults were for drug-related skin reactions, with antibiotics frequently identified as the culprits.
July 2015 in “Actas Dermo-Sifiliográficas” A woman experienced excessive hair growth after using a hair loss treatment with minoxidil.
January 2015 in “Our Dermatology Online” This study found that intralesional triamcinolone was the most effective treatment for achieving over 50% hair regrowth in alopecia areata patients, especially those with single patches.
January 2015 in “Przegla̧d dermatologiczny” This study observed that excimer light therapy, intralesional triamcinolone, and topical 5% minoxidil all had differing levels of effectiveness in treating alopecia areata, with variable results noted among treatments.
This study evaluated the accuracy of the HairCheck device, a cross-section trichometer, and concluded that it effectively measures changes in hair diameter and density for assessing alopecia progression and treatment response.
November 2005 in “Journal of Investigative Dermatology Symposium Proceedings” This review discusses the latest findings presented at the 4th Intercontinental Meeting of Hair Research Societies, covering advances in hair follicle biology, genetic bases for hair disorders, and potential new therapeutic approaches, but it reports no original study results.
176 citations
,
August 2015 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” This study identified a distinct cytokine activation signature in alopecia areata, involving TH2, TH1, IL-23, and IL-9/TH9 pathways, suggesting potential targeting strategies similar to those in psoriasis and atopic dermatitis.
112 citations
,
January 2014 in “Molecular and cellular therapies” This review summarizes the current understanding of Wnt signaling in relation to its roles in tissue regeneration and cancer progression and discusses recent medical advancements targeting this pathway for therapeutic purposes.
66 citations
,
February 2015 in “Cell & tissue research/Cell and tissue research” This review explores the mechanisms of hair cell death due to factors like noise, ototoxic drugs, and aging and reports no conclusive clinical results; ongoing research may eventually enable preventive treatments for hearing loss.
33 citations
,
January 2011 in “Elsevier eBooks” This article reviews the complexity and diverse manifestations of systemic lupus erythematosus, highlighting potential genetic, hormonal, and environmental factors in its pathogenesis without presenting new clinical findings.
30 citations
,
December 2017 in “Clinical, Cosmetic and Investigational Dermatology” This study found significant differences in hair density, non-vellus hair diameter, and percentage of miniaturized hair between normal women and those with female pattern hair loss, particularly in the midscalp and parietal areas.
29 citations
,
January 2021 in “Translational Psychiatry” This study found that certain gene sets, including those involved in ligand-gated ion channel signaling and cell adhesion, are associated with Tourette syndrome, suggesting a potential neurobiological basis for the disorder.
28 citations
,
November 2017 in “Skin appendage disorders” This paper proposes a systematic approach to evaluating scalp itch using the SCALLP acronym and highlights the importance of classifying cases based on the presence of dermatological lesions and hair loss, but it reports no new clinical findings.