Tofacitinib Citrate Alleviates Alopecia Universalis Symptoms in Recent Case Study

    April 2016 in “ Journal of the American Academy of Dermatology ”
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    TLDR Tofacitinib helped a person with total body hair loss grow hair again without bad side effects.
    In a case study from 2016, a patient with alopecia universalis (AU), a severe form of alopecia areata characterized by complete body hair loss, was treated with tofacitinib citrate, a small molecule kinase inhibitor targeting the JAK1/3 pathway. The patient was prescribed a dosage of 5 mg twice daily and observed over eight months. Beard growth was noted at three months, and by six months, hair growth was observed throughout the body. At eight months, the patient experienced the regrowth of scalp hair, eyelashes, and eyebrows. The chronology of hair regrowth suggested that tofacitinib was effective in alleviating the symptoms of AU without adverse side effects. However, the possibility of spontaneous remission was acknowledged, and further studies were recommended to confirm the safety and efficacy of tofacitinib for treating AU.
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      in Chat  3 upvotes 4 months ago
      A 23-year-old male is experiencing diffuse hair loss and miniaturization, possibly due to high IGE levels after using tofacitinib. He seeks advice and has not yet consulted a dermatologist.

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      in Treatment  1 upvotes 2 weeks ago
      The user is using finasteride 1mg every other day and seeks a topical solution excluding minoxidil. They are considering various combinations of ingredients like finasteride, dutasteride, and tofacitinib, with options for nourishing oils and other additives.

      community Topical solution recommendation

      in Product  1 upvotes 2 weeks ago
      The user is using finasteride 1mg every other day and seeks a topical solution to complement it, excluding minoxidil. They are considering various combinations of ingredients like finasteride, dutasteride, and tofacitinib, with options for nourishing oils and other additives.

      community 22F. Should I even bother getting a biopsy? Is there any point?

       8 upvotes 9 years ago
      A woman who has been experiencing hair loss for several years, and her question of whether there is any benefit to getting a biopsy to check if it's AGA or diffuse alopecia areata when no cure or very effective treatment exists. Treatments such as spironolactone and Minoxidil/finasteride/RU58841 have previously been discussed.

      community No hair, don't care! [24/F] :)

       59 upvotes 9 years ago
      A woman with alopecia universalis shares her positive experience of being bald, finding it freeing and less worrisome. She also discusses her skincare routine using Korean products.

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