32 citations
,
December 2013 in “Biological & Pharmaceutical Bulletin” In this study, rice bran supercritical CO2 extract demonstrated potential to promote hair growth in mice, increasing hair follicles and growth factor expression, similarly to 3% minoxidil.
24 citations
,
April 2007 in “European Journal of Pharmaceutics and Biopharmaceutics” This study found that artocarpin delivered via alginate/chitosan microparticles effectively suppressed the growth of hamster flank organs compared to artocarpin in solution form, without significant systemic effects.
23 citations
,
January 2017 in “Journal of Oleo Science” This review discusses the use of supercritical carbon dioxide for extracting rice bran oil, noting its advantages over conventional methods for preserving nutrients and antioxidants, but provides no new experimental results.
22 citations
,
August 2011 in “Journal of Supercritical Fluids” In this study, fraction No. 3 of Oryza sativa bran extract demonstrated high unsaturated fatty acid content and significant 5α-reductase inhibition, suggesting potential for developing anti-androgenic alopecia products.
22 citations
,
August 2009 in “Evidence-based Complementary and Alternative Medicine” This study found that a composition including Serenoa repens extract and anti-inflammatory agents effectively suppressed inflammation-related gene expression in a keratinocyte model, suggesting a potential dual strategy for treating androgenetic alopecia.
22 citations
,
March 2009 in “Journal of Natural Medicines” This study found that Erica multiflora extract promotes hair growth by enhancing dermal papilla cell activity and shifting hair follicles from the telogen to the anagen phase in both in vitro and in vivo models.
21 citations
,
January 2018 in “Anticancer Research” This study suggests that NBCCS and BFHS may be the same genetic condition, which could help improve identification and management of misdiagnosed cases with specific surveillance strategies.
18 citations
,
December 2020 in “Frontiers in cell and developmental biology” This study found that extracellular vesicles from low-passage dermal papilla cells may activate hair growth by delivering miR-140-5p, which downregulates BMP2 signaling, suggesting potential therapeutic targets for alopecia.
15 citations
,
August 2017 in “International Journal of Molecular Medicine” This study reported that Panax ginseng extract significantly inhibited DKK-1-induced catagen-like changes in human hair follicles by promoting cell proliferation and reducing apoptosis, suggesting it may help mitigate hair loss associated with DKK-1.
15 citations
,
January 2013 in “Journal of Cutaneous and Aesthetic Surgery” This study observed that direct hair transplantation, as a modification of follicular unit extraction, was effective in improving baldness in the majority of treated male patients.
14 citations
,
March 2017 in “Plastic and reconstructive surgery. Global open” In this study, various types of minor hair follicle damage were observed during follicular unit extraction, with paring and hair bulb injury being more apparent under microscopic examination.
13 citations
,
June 2020 in “Stem Cells International” In this study using a mouse model, ECM/SVF-CM, derived from adipose-derived stem cells, was observed to stimulate hair growth more effectively than SVF-CM by promoting cell proliferation, neovascularization, and anagen induction, which may support its potential as an improved treatment for hair loss.
13 citations
,
November 2018 in “Annals of Plastic Surgery” This article presents a surgical approach for nonshaven follicular unit extraction in hair transplantation, describing its application across various conditions with an average graft transection rate of 8.2%.
13 citations
,
August 2002 in “Dermatologic Surgery” This paper introduces Follicular Unit Extraction and reports the FOX Test can identify suitable candidates, with about 25% of patients being ideal and 35% being good candidates for the procedure.
13 citations
,
July 2022 in “Frontiers in cell and developmental biology” This review discusses the potential of cell-derived nanovesicles as innovative treatment strategies for hair growth and provides no new clinical results; the authors emphasize the need for further understanding of their mechanisms.
12 citations
,
September 2014 in “Journal of Food Science and Nutrition” This study suggests that Platycarya strobilacea extract promotes hair growth in mice by enhancing stem cell factor expression, reducing mast cell numbers, and increasing cytokines associated with hair growth.
12 citations
,
October 2017 in “Journal of Cosmetic Dermatology” This study found that plasma rich in growth factors (PRGF) as an adjuvant to follicular unit extraction (FUE) surgery may enhance hair graft performance and reduce post-surgical inflammation and pain in hair loss patients.
11 citations
,
October 2018 in “The Journal of Dermatology” This study suggests that decorin may help maintain hair follicle stem cells and its reduced expression could contribute to age-related hair loss.
11 citations
,
April 2016 in “Dermatologic Surgery” This study concluded that to accurately calculate the transection rate in follicular unit extraction, it's essential to account for both extracted and hidden transections, which differ based on surgeon expertise.
10 citations
,
January 2009 in “Scientific Electronic Library Online (São Paulo Research Foundation, Latin American and Caribbean Center on Health Sciences Information, Conselho Nacional de Desenvolvimento Científico e Tecnológico)” This study found that Eclipta alba extracts exhibit significant antimicrobial activity against various human pathogens, including antibiotic-resistant strains, suggesting potential use in treating infectious diseases.
10 citations
,
January 2010 in “Veterinary pathology” This study found that a newly identified mutation in the hairless gene in mice led to decreased Hr mRNA levels and changes in gene expression related to hair follicle development.
8 citations
,
September 2017 in “Journal of Natural Medicines” This study reported that the n-butanol fraction of Perilla frutescens extract, particularly rosmarinic acid, showed potential for hair regrowth and anti-androgenic activity in male mice, suggesting it as a possible treatment for androgenetic alopecia.
7 citations
,
January 2015 in “Biological & Pharmaceutical Bulletin” This study found that a 16-week dermal application of rice bran extract significantly increased hair density and diameter in male androgenic alopecia patients without causing adverse reactions.
7 citations
,
January 2010 in “Pharmacognosy Research” This study evaluated the hair growth potential of a microbial biotransformed extract of tobacco leaves in male albino wistar rats, but no new results are provided in the abstract.
6 citations
,
October 2018 in “Bioelectromagnetics” This study found that treating a 3D hair dermal papilla model with rice bran extract and electromagnetic fields increased melanogenesis, suggesting potential for vitiligo and white hair therapies.
4 citations
,
March 2020 in “Journal of Cosmetic Dermatology” This study found that Plumbago zeylanica extract and its component plumbagin may help prevent androgenetic alopecia by promoting dermal papilla cell growth and reducing SRD5A2 expression.
4 citations
,
August 2017 in “Cosmetics” This study observed that Biota orientalis L. leaf extract may promote hair growth and suppress sebum production in human cells, suggesting potential benefits for hair restoration.
3 citations
,
April 2021 in “Journal of Cosmetic Dermatology” In this study, the researchers found that a manual micrometer caliper is a reliable tool for planning hair transplant surgery and accurately measures the short axis of the hair shaft.
2 citations
,
January 2020 in “BioMed Research International” This study found that Phaeodactylum tricornutum extract enhanced hair follicle cell proliferation, indicated by increased keratin and ERK1/2 signaling, suggesting its potential for hair care applications.
2 citations
,
April 2016 in “Más dermatología” This study found that the dietary supplement RJ-SP4AGA significantly improved hair growth and reduced hair loss in post-menopausal women with androgenetic alopecia over 16 weeks.