26 citations,
May 2012 in “Cellular and Molecular Life Sciences” NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.
The CD4 protein may play a role in the behavior of certain skin cells, affecting their growth, movement, and differentiation.
40 citations,
January 2016 in “Stem Cells International” Mesenchymal stem cells help improve wound healing by reducing inflammation and promoting skin cell growth and movement.
113 citations,
June 2015 in “Stem Cell Research & Therapy” Wnt and Notch signaling help wound healing by promoting cell growth and regulating cell differentiation.
1 citations,
July 1973 in “British Journal of Dermatology” The document concludes that secondary syphilis cases are increasing and often misdiagnosed, pityriasis rubra pilaris can be distinguished from psoriasis by skin cell features, and different skin layers produce specific components during skin repair.
9 citations,
July 2007 in “Circulation Research” Defects in certain proteins cause major heart abnormalities during early development.
2 citations,
January 2008 in “Elsevier eBooks” Humans have limited regenerative abilities, but new evidence shows the adult brain and heart can regenerate, and future treatments may improve this by mimicking stem cell environments.
44 citations,
December 1991 in “Annals of the New York Academy of Sciences” EGF and FGF help hair growth by affecting cell differentiation and fiber growth.
August 2024 in “Receptors” Vitamin D receptor is crucial for skin wound healing.
Stem cells regenerate tissues and their behavior varies by environment, suggesting the hematopoietic system model may need revision.
232 citations,
January 2013 in “Nature Cell Biology” Understanding where cancer cells come from helps create better prevention and treatment methods.
62 citations,
October 2017 in “JAMA facial plastic surgery” Condensed nanofat with fat grafts effectively improves atrophic facial scars.
38 citations,
June 2019 in “International Journal of Molecular Sciences” Tiny particles called extracellular vesicles could help with skin healing and hair growth, but more research is needed.
32 citations,
March 2014 in “PLOS ONE” Mice lacking fibromodulin have disrupted healing patterns, leading to abnormal skin repair and scarring.
25 citations,
December 1992 in “Seminars in cell biology” Skin stem cells are maintained by signals from nearby cells and vary in their ability to renew and mature.
22 citations,
April 1998 in “Dermatologic Clinics” Interferons are effective for some skin conditions and cancers, but can have side effects and need more research for optimal use.
20 citations,
September 2016 in “International Journal of Cancer” Men with male pattern baldness have a higher risk of certain skin cancers, especially on the scalp.
12 citations,
May 2001 in “British journal of dermatology/British journal of dermatology, Supplement” A rare benign skin tumor showed unusual features of sebaceous and sweat glands, important for correct diagnosis.
11 citations,
October 2014 in “Journal of Investigative Dermatology” Genetic mutation and carcinogen treatment are both needed for skin cancer to develop in these specific mice.
7 citations,
January 2018 in “Journal of Tissue Viability” An 80-year-old patient grew new hair on a wound, showing that elderly people can still regenerate hair.
7 citations,
August 2017 in “PloS one” Key genes linked to hair growth and cancer were identified in hairless mice.
1 citations,
January 2016 in “Elsevier eBooks” The document concludes that identifying the specific cells where skin cancers begin is important for creating better prevention, detection, and treatment methods.
July 2017 in “British Journal of Dermatology” The document concludes that scalp conditions have various causes and can present in many different ways.
May 2002 in “Australasian Journal of Dermatology” Finasteride is effective for male hair loss, teledermatology is accurate and accepted, and cyclosporin helps treat toxic epidermal necrolysis.
October 1982 in “American Journal of Nursing” Wound healing is a complex process involving different cells and stages, leading to scar tissue formation and strength increase over time.
65 citations,
June 2020 in “Stem Cell Research & Therapy” Certain immune system proteins are important for skin healing but can cause problems if there are too many of them.
45 citations,
January 2010 in “Journal of Investigative Dermatology” The S100A4 protein is more common in psoriatic skin and could be a target for treating psoriasis.
35 citations,
August 2021 in “npj Regenerative Medicine” Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.
30 citations,
June 2014 in “Seminars in Immunology” Future research on ectodysplasin should explore its role in diseases, stem cells, and evolution, and continue developing treatments for genetic disorders like hypohidrotic ectodermal dysplasia.
7 citations,
January 2023 in “Frontiers in Cell and Developmental Biology” Caspases are enzymes important for both cell death and various non-lethal cell functions, affecting head development and hair growth, with different caspases playing specific roles.