research Host Genetic Susceptibility and Impacts of Dietary Factors on COVID-19
Certain genes and nutrients like vitamin D, zinc, and omega fatty acids affect COVID-19 severity and infection risk.
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research Discerning Patient Perspectives Towards Specific Treatments of Alopecia Areata Using Artificial Intelligence
Patients using social media have mixed feelings about alopecia treatments, noting hair growth but also frustration with treatment recurrence.
research Dermatological Manifestations of COVID-19: A Brief Review
COVID-19 can cause skin issues like "COVID toes," rashes, hair loss, and hand eczema, and dermatologists are important for recognizing these signs.
research Patient and Device Generated Variability in Platelet-Derived Growth Factors During Platelet-Rich Plasma Therapy for Hair Loss
Differences in growth factors in platelet-rich plasma therapy for hair loss can vary between patients and can be influenced by the devices used, possibly leading to inconsistent results.
research The Itchy Scalp: An Overview of Scalp Pruritus and Its Management
Up to half of people experience itchy scalp, often due to skin conditions like seborrheic dermatitis or psoriasis, and treatments vary based on the specific cause.
research Nicotinic Acid Suppresses Sebaceous Lipid Synthesis of Human Sebocytes via Activating Hydroxycarboxylic Acid Receptor 2 (HCA2)
Nicotinic acid reduces excessive oil production in skin cells by activating a specific receptor, which could help treat acne.
research Presence of Psoriasis in Areas of Balding in Patients with Both Androgenic Alopecia and Scalp Psoriasis
Men with both baldness and scalp psoriasis often don't have psoriasis on bald spots.
research Editors' Picks
ANp63 is crucial for skin integrity, new filaggrin gene mutations link to eczema, hair can regrow from non-stem cells, sunburns are increasing, and glucocorticoids help treat skin allergies by affecting immune cells.
research Drug Discovery Today: Therapeutic Strategies - 2006 Editorial
The 2006 editorial concluded that immunotherapy was advancing with new drugs, focusing on specific biological therapies and convenient oral treatments, and highlighted the importance of partnerships and new regulations in the field.
research Hair Cosmetic Alterations
The document concludes that individualized treatments for hair issues are effective, certain hair changes can indicate neurocutaneous diseases, specific lotions improve skin health, laser hair removal works but needs more study on long-term effects, men's cosmetics are diverse, peeling is effective but can have side effects, and facial pigmentation is often due to overactive skin cells.
research Pegylated Liposomal Doxorubicin: Metamorphosis of an Old Drug into a New Form of Chemotherapy
Doxil is an effective, modified chemotherapy drug with a unique toxicity profile and shows promise in treating certain cancers.
research The Dynamics of the Skin’s Immune System
The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.
research Zinc Therapy in Dermatology: A Review
Zinc is effective for treating various skin conditions, including warts and acne.
research Prevalence and Associated Factors of Skin Diseases in Aged Nursing Home Residents: A Multicentre Prevalence Study
Nearly all elderly nursing home residents had a skin disease, with dry skin being the most common.
research Spatiotemporal Control of CRISPR/Cas9 Gene Editing
The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.
research Combined Deletion of the Vitamin D Receptor and Calcium-Sensing Receptor Delays Wound Re-Epithelialization
Removing vitamin D and calcium receptors in mice skin cells slows down skin wound healing.
research Dermatological Manifestations Associated with COVID-19: A Comprehensive Review of the Current Knowledge
COVID-19 can cause various skin issues, including rashes and hair loss, which usually heal on their own and don't always indicate severe illness.
research Cosmetic Devices Based on Active Transdermal Technologies
Active transdermal technologies in cosmetics help deliver skin treatments effectively, but their safety and effectiveness depend on skin type and treatment choice.
research Physiopathological Role of the Enzymatic Complex 5α-Reductase and 3α/β-Hydroxysteroid Oxidoreductase in the Generation of Progesterone and Testosterone Neuroactive Metabolites
The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.
research Focal and Generalized Alopecia in Cats: Causes, Diagnosis, and Treatment
The document concludes that hair loss in cats is caused by various factors, including allergies, mites, infections, and hormonal issues, with treatments varying accordingly.
research Gender Differences in Production and Circulating Levels of Sex Hormones and Their Impact on Aging Skin
Men and women experience skin aging differently due to changes in sex hormone levels with age.
research Tribuloside Acts on the PDE/cAMP/PKA Pathway to Enhance Melanogenesis, Melanocyte Dendricity and Melanosome Transport
Tribuloside can increase skin pigmentation by enhancing melanin production and distribution.
research Impact of Stem Cells on Reparative Regeneration in Abdominal and Dorsal Skin in the Rat
Abdominal skin heals faster than dorsal skin because it has more stem cells.
research Cannabinoid Signaling in the Skin: Therapeutic Potential of the Cutaneous Cannabinoid System
Cannabinoids may help treat various skin conditions.
research Toward Understanding Scarless Skin Wound Healing and Pathological Scarring
Scarless healing is complex and influenced by genetics and environment, while better understanding could improve scar treatment.
research Small Molecule Wnt Pathway Inhibitor (SM04755) as a Potential Topical Psoriasis Treatment
SM04755 may be an effective topical treatment for psoriasis.
research Expression of Hypothalamic-Pituitary-Thyroid Axis Related Genes in Human Skin
Thyroid-related genes are active in skin cells and may affect autoimmune conditions.
research Alopecia Areata and the Gut: The Link Opens Up for Novel Therapeutic Interventions
Gut health may influence Alopecia Areata, suggesting new treatments.
research The Human Skin Microbiome in Selected Cutaneous Diseases
Changes in skin microbes play a role in some skin diseases and could lead to new treatments.
research The Role of Extracellular Vesicles in Cutaneous Remodeling and Hair Follicle Dynamics
Tiny particles called extracellular vesicles could help with skin healing and hair growth, but more research is needed.