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Botanical extracts are increasingly important in cosmetics and drugs for their effectiveness and safety, backed by traditional use and scientific evidence.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Wild African goats have genetic adaptations for surviving harsh desert conditions.

ADSC-derived extracellular vesicles show promise for skin and hair regeneration and wound healing.

The enzyme DHHC13 is essential for healthy hair and skin, and its deficiency leads to hair loss and skin problems.

Cell death shapes skin stem cell environments, affecting inflammation, repair, and cancer.

PPARγ is crucial for skin health but can have both beneficial and harmful effects.

Non-liganded Vitamin D Receptor is crucial for healthy skin and hair.

AcSDKP may help prevent skin and hair aging and promote their growth.

Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.

Testosterone can cause acne and male-pattern baldness, affects hair growth in men and women, and makes male skin more sensitive.

Lipid nanoparticles improve drug delivery through the skin, offering stability, controlled release, and better compatibility with skin.

Sensitive skin is often caused by nerve fibers and environmental factors, and can be managed with mild skincare and professional advice.

Glycerol is essential for skin hydration in mice without sebaceous glands.

Skin structure complexity and variability are crucial for assessing skin toxicity in safety tests.

The skin is vital for protection, temperature control, fluid balance, immunity, and sensing, with damage affecting daily life and mental health.

An intact skin barrier is crucial to prevent infection in cases of tether-induced tenosynovitis.

Hair follicles evolved from oil glands, with hair aiding secretion transport.

Dandruff is linked to increased T cells and weakened immune protection in hair follicles.

Mice with too much Claudin-6 have skin barrier problems and abnormal hair growth.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Marine microbes could be used in cosmetics for sun protection, skin care, and possibly preventing hair loss.

COVID-19 may harm male fertility and damage the reproductive system.

Hair is important for protection, social interaction, and temperature control, and is made of a growth cycle-influenced follicle and a complex shaft.

JAM-A helps hair regrowth in alopecia areata by protecting VCAN in skin cells.

Inducing survivin in normal tissues can protect against radiation damage.

Intestinal intraepithelial lymphocytes are crucial for gut immunity and maintaining the mucosal barrier.

Thyroid disease can cause skin, hair, and nail problems, and treating the thyroid condition often improves these symptoms.

Applying a DNA vaccine to skin with active hair growth boosts immune response and protection against anthrax in mice.