research Three-Dimensional Proteome-Wide Scale Screening for the 5-Alpha Reductase Inhibitor Finasteride: Identification of a Novel Off-Target
Finasteride may affect PNMT, causing side effects.
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research The Role of Histone Demethylases in Disease
Histone demethylases play a key role in the development of many diseases and may be targets for treatment.
research Comparison of Three Different Lactic Acid Bacteria-Fermented Proteins on RAW 264.7 Osteoclast and MC3T3-E1 Osteoblast Differentiation
Fermented soy protein may help prevent bone loss by affecting bone cell activity.
research Historical Archives: Dermatological Topics and Figures
The document reviews key historical figures and discoveries in dermatology.
research Coactivator MED1 Ablation in Keratinocytes Results in Hair-Cycling Defects and Epidermal Alterations
Deleting MED1 in skin cells causes hair loss and skin changes.
research Topical Retinoids: Therapeutic Mechanisms in the Treatment of Photodamaged Skin
Topical retinoids effectively improve photodamaged skin.
research The Application Prospects of Honokiol in Dermatology
Honokiol from Magnolia plants may be beneficial for treating various skin conditions and promoting hair growth.
research Influence of Knowledge and Beliefs on Consumption of Performance Enhancing Agents in North-Western Saudi Arabia
More knowledge about the risks of performance-enhancing agents leads to less use in north-western Saudi Arabia.
research Recent Developments in Luteolin-Loaded Nanoformulations for Enhanced Anti-Carcinogenic Activities: Insights from In Vitro and In Vivo Studies
Nanoformulations improve luteolin's effectiveness as a cancer treatment.
research Vitamin D and the Skin: Focus on a Complex Relationship
Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.
research Knuckle Hyperpigmentation as a Preliminary Marker of Vitamin B12 Deficiency: A Case Series
Knuckle darkening can be an early sign of vitamin B12 deficiency.
research Vitamin B12 Deficiency: A Rare Cause of Excessive Daytime Sleepiness
Vitamin B12 deficiency can rarely cause excessive daytime sleepiness.
research Preventing the Development of Complex Regional Pain Syndrome After Surgery
Preoperative pain assessment, regional anesthesia, and vitamin C can help prevent CRPS after surgery.
research Role of Vitamin D and Calcium Signaling in Epidermal Wound Healing
Vitamin D and calcium are important for quick and effective skin wound healing.
research Vitamin D and the Skin: Physiology and Pathophysiology
Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.
research Hairless Modulates Ligand-Dependent Activation of the Vitamin D Receptor-Retinoid X Receptor Heterodimer
Hairless protein can both repress and activate vitamin D receptor functions, affecting gene regulation.
research Ultraviolet B Irradiation Increases the Expression of Inflammatory Cytokines in Cultured Sebocytes
UV-B light increases inflammation-related substances in acne-related skin cells.
research Novel ABCD1 Gene Mutation in Adrenomyeloneuropathy with Hypoplasia and Agenesis of the Corpus Callosum
Researchers found a new ABCD1 gene mutation linked to a rare brain and nerve disorder with unusual brain changes.
research White Monkey Syndrome in Infant Baboons (Papio Species)
Infant baboons suffered from zinc poisoning due to poor cage conditions.
research Addressing Androgenetic Alopecia: A Complex Disorder with a Multilateral Treatment Strategy
Treating hair loss effectively may require a multi-sided approach, using different treatments together, and topical treatments could be more effective and safer than oral ones.
research The Role of the Vitamin D Receptor in the Epidermal Stem Cell Response to Wounding
Vitamin D receptor is crucial for skin wound healing.
research Endocrine Control of Benign Prostatic Hyperplasia
Hormones and metabolism play a complex role in prostate enlargement, and more research is needed to improve diagnosis and treatment.
research Hormones and Skin: A Never Ending Love Story
Hormones significantly affect skin health, with vitamin D playing a key role.
research Human Hair Follicle: An Update on Biology and Perspectives in Hair Growth Disorders Treatment
New treatments for hair growth disorders are needed due to limited current options and complex hair follicle biology.
research Suppression of Vitamin D Receptor and Induction of Retinoid X Receptor Alpha Expression During Squamous Differentiation of Cultured Keratinocytes
As skin cells mature, vitamin D receptor levels decrease while retinoid X receptor α levels increase.
research Regulation of the Human Hair Cycle
The conclusion is that effectively treating hair disorders is difficult due to the complex factors affecting hair growth and more research is needed to improve treatments.
research In This Issue
Alexander the Great's engineers built a causeway using a natural sand bridge, some tiger moths avoid bats by mimicking toxic relatives' sounds, early metabolism and RNA enzymes support the ancient RNA world theory, and vitamin D is crucial for hair growth and its absence can cause baldness.
research Immunology and Genetics
The document concludes that Borrelia afzelii causes a skin condition in France, a gene is linked to hair loss in Caucasian women, and various genetic mutations affect skin diseases.
research Skin Diseases Due to Endocrine Alterations
Hormone imbalances can cause skin diseases, and understanding these links is important for diagnosis and treatment.
research Advances in Psoriasis Therapy
New psoriasis treatments are effective but come with side effects and risks.