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The new chemotherapy combination of WP 631 and Epothilone B shows enhanced effectiveness against ovarian cancer but requires more research on its safety.

Phosphorylation of certain parts of the PIN3 protein is crucial for its role in plant root growth and response to gravity.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

CD4+ skin cells may be precursors to basal cell carcinoma.

Basal cell carcinomas have much higher levels of Vitamin D3 receptors compared to healthy skin.

Smart biomaterials that guide tissue repair are key for future medical treatments.

New therapies are being developed that target integrin pathways to treat various diseases.

Scientists can use engineered microbes to make L-aspartate and related chemicals, but there's still room to improve their efficiency.

Near-infrared LED light improves skin rejuvenation and hair growth better than white LED light.

Wnt/β-catenin signaling is important for keeping skin cell attachment structures stable.

Scientists can grow human hair follicle stem cells in a lab without changing their nature, which could help treat hair loss.

Mitoxantrone is effective for treating acute leukemia, especially in older patients, with a lower risk of heart damage.

Targeting NETs may help reduce fibrosis in Crohn's disease.

The TRPV3 ion channel is important for skin and hair health and could be a target for treating skin conditions.

The hydrogel speeds up burn wound healing and promotes tissue regeneration.

Hairless protein is key for hair growth, cell differences cause gene expression variation, and the N-end rule pathway senses nitric oxide for protein breakdown.

Small proline-rich proteins and trichohyalin help make epithelial tissues tougher and more flexible.

Keratin proteins are consistent across different hair types from the same person.

Harlequin mutant mice have hair loss due to low AIF protein levels and retroviral element activity.

Celsr1 is crucial for skin cell alignment, while Celsr2 has little effect on this process.

Gelatin microspheres with stem cells speed up healing in diabetic wounds.

Mouse profilaggrin helps in skin cell differentiation and may be involved in calcium signaling.

The conclusion is that the nuclear lamina and LINC complex in skin cells respond to mechanical signals, affecting gene expression and cell differentiation, which is important for skin health and can impact skin diseases.

Keratin is crucial for keeping skin cells healthy and its changes can lead to diseases and affect cell behavior.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

Hair's strength and flexibility come from its protein structure and molecular interactions.

Some brain cancer cells avoid immune system detection, and certain treatments could target this to slow their growth; also, certain fat cell precursors help regenerate hair and skin after injury.

Scientists made a mouse that shows how a specific protein in the skin changes and affects hair growth and shape.

Researchers found a specific immune receptor in patients that causes severe skin reactions to a drug.

CXXC5 is a protein that controls cell growth and healing processes, and changes in its activity can lead to diseases like cancer and hair loss.