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Finasteride's two forms have different stability based on temperature and pressure.

Finasteride slowly binds to 5-alpha-reductase, affecting enzyme stability and inhibitor potency.

Finasteride may treat baldness but less effective for those with 5α-reductase deficiency.

Androgen hormones cause hair follicle scarring in hair loss, and finasteride helps reduce it.

Desolvation of finasteride depends on environment and technique.

The more lipophilic the progesterone derivative, the better it binds to androgen receptors and has antiandrogenic effects.

New treatments for enlarged prostate are being developed, some of which may be more effective than current medications.

Some IBD patients on anti-TNFs developed severe skin issues, but ustekinumab helped.

The research found that compound 6, a newly created steroid, is more effective at inhibiting 5α-reductase (an enzyme) than current treatments, suggesting it could be a better option for treating urinary tract symptoms in men.

Finasteride's effect on hair loss and prostate enlargement depends on its binding to an enzyme, with maximum impact at 0.2 mg dose.

The research shows that hydrogen bonds greatly affect the crystal structure of a Finasteride derivative.

Compound 3 protects the heart from damage by activating A1-adenosine receptors.

The document explains different types of hair loss, their causes, and treatments, and suggests future research areas.

Some patients on immunosuppressants had a weaker immune response to the Sinovac-CoronaVac COVID-19 vaccine.

The NUDT15 gene variant causes severe side effects from azathioprine in some Indian patients.

Four-amino acid part makes enzyme sensitive to finasteride.

Finasteride effectively blocks rat enzymes, but with varying methods and strength.

Finasteride poorly inhibits type 1 5AR, affecting its effectiveness.

LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.

Finasteride's molecular and crystal structures help develop new drug formulations.

Finasteride metabolites found in pigs match human studies, making pigs a valid model for human drug research.

Bolandiol, a synthetic steroid, builds muscle and bone without greatly affecting sex glands, and works differently from other hormones.

Female hair loss is often hereditary and can be treated with medication, hair transplants, and lasers.

Accurate method measures finasteride levels in human plasma using gas chromatography-mass spectrometry.

New treatments for lupus show promise, but more research is needed, especially for children.

Finasteride metabolism varies by age, sex, and P450 inducers, with males processing it faster.

New method accurately measures finasteride in tablets and bulk.

Finasteride doesn't effectively treat hair loss in postmenopausal women.

Finasteride temporarily lowers male rat fertility without affecting libido.

Researchers found new potential but less potent rat enzyme inhibitors using a 3D model.