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This study suggests that inducible transgenic mice showing hair follicle changes similar to telogen effluvium in humans might serve as a useful model for understanding this type of hair loss.

In this study, overexpression of YAP1 was found to promote adipogenic differentiation of goat adipose-derived mesenchymal stem cells by up-regulating LATS2 expression and activating the Hippo pathway's negative feedback loop.

In this study, researchers found that a PER3 gene SNP may be pathogenic for a new subtype of dyschromatosis universalis hereditaria, especially when combined with a SASH1 mutation.

This review discusses the dual role of apoptotic vesicles in disease and therapy, emphasizing their potential in cancer treatment and tissue regeneration, but reports no new results.

This article reviews advancements in understanding skin regeneration and suggests that bioengineering skin surrogates may soon enhance treatments for skin trauma, but it presents no new clinical findings.

This review discusses the complex role of the EDA pathway in vertebrate skeletal development, emphasizing its interaction with other morphogenic pathways to influence skeletal diversity, but reports no new experimental results.

Thyroid disease can cause hair loss and treating thyroid problems might help with hair disorders.

This study found that the dynamic characteristics of both cerebrovascular carbon dioxide reactivity and central respiratory chemoreflex decrease in the high frequency range and are not modified by exercise.

This review discusses the metabolic and physiological mechanisms that maintain hematopoietic stem cell function, particularly focusing on oxygen and energy homeostasis, but it reports no new experimental results.

This study demonstrates that warming hands can restore normal blood flow in patients with systemic sclerosis, making their response to cooling similar to that of healthy controls.

This study observed that in adult mice, a cell-autonomous size control mechanism involving the RB pathway determines the timing of S phase entry in epidermal stem cells based on their size, while external microenvironment factors influence growth rates but not this intrinsic coupling.

In this study, researchers observed that blood vessel maturation in mice involves neonatal endothelial cells expanding the capillary network through vessel regression and angiogenesis, with adult cells later maintaining stability and repair through specific signaling pathways.

This chapter discusses the concepts of regeneration and homeostasis, noting that in vertebrates, regeneration is limited to certain tissues like liver, blood, and bone.

Low oxygen and metabolic changes help organoids grow and repair tissues.

This study observed that, in mouse ear epidermal stem cells, a cell-autonomous size control mechanism involving the RB pathway dictates S phase entry timing based on cell size, despite external environmental variations affecting growth rates.

In this study, researchers found that a positive feedback loop involving Ca 2+ and RHD2 NADPH oxidase-derived ROS helps maintain growth sites, crucial for root hair development and cell shape in Arabidopsis thaliana.

In this study, a deep neural network model called regX was developed to prioritize driver regulators for cell state transitions by incorporating gene-level regulation and interactions, showing potential therapeutic targets in type 2 diabetes and hair follicle development when applied to single-cell multi-omics data.

This review discusses the heterogeneity of Tregs in normal and tumor environments, emphasizing the complexity of targeting tumor-resident Tregs while maintaining systemic immune tolerance, but reports no new findings.

This study highlights the role of innate immunity and purinergic signaling in regulating hematopoiesis and hematopoietic stem/progenitor cell specification. The researchers observed that these ancient pathways operate both paracrinally and autocrinally within HSPCs, maintaining their developmental function throughout evolution.

This review examines regulatory mechanisms of quiescent stem cells in tissue homeostasis, drawing on observations from the intestine and other self-renewing tissues, without presenting new data.

The researchers reported that VEGF increases vascular permeability in mesenteric microvessels of anaesthetized frogs through specific cellular pathways involving tyrosine autophosphorylation and PLC activation.

In this study, researchers using the hair paradigm highlighted how periodic patterning and compartmentalization enable diverse regenerative behaviors, including region-specific renewal cycles and emergent properties like regenerative waves in organ populations.

In this theoretical study, the authors developed a computational model to explore whether a reaction-diffusion process could explain the signal inducing axolotl spinal cord regeneration, proposing that regeneration control depends on cell sensitivity to the signal and its diffusion characteristics.

This paper proposes a model integrating regulatory T cells and mesenchymal stem/stromal cells to enhance understanding of peripheral immune tolerance, suggesting their combined roles in immune regulation, autoimmunity pathophysiology, and potential MSC-based therapies.

This study demonstrates that neural stem cells in the adult vertebrate brain coordinate their division decisions using delayed local feedback mechanisms, involving Notch-mediated inhibition and dispersion effects, to maintain population homeostasis.

Regulatory T cells help prevent autoimmunity and have potential for treating autoimmune diseases.

This review discusses molecular regulatory circuitry in organ regeneration, using skin regeneration examples, and reports no new experimental results; the authors propose that understanding this circuitry might aid in developing therapeutic strategies.

This review discusses the role and regulation of quiescent adult stem cells in tissue maintenance and repair, focusing on molecular mechanisms and their implications for regenerative medicine, but reports no new clinical results.

This review discusses the multiple layers of environmental controls on hair stem cell homeostasis and suggests that targeting these layers could offer safer regenerative medicine therapies without directly using stem cells.

This study found that a positive feedback loop involving RHD2, reactive oxygen species, and calcium ions helps maintain root hair growth sites and influences cell shape in Arabidopsis thaliana.