52 citations,
October 1999 in “Developmental Dynamics” Mutations in the hairless gene in mice affect its expression and lead to a range of developmental issues in multiple tissues.
50 citations,
October 2009 in “Clinical Endocrinology” Hair loss in young men linked to higher risk of insulin resistance and metabolic issues.
38 citations,
June 2019 in “International Journal of Molecular Sciences” Tiny particles called extracellular vesicles could help with skin healing and hair growth, but more research is needed.
38 citations,
July 1998 in “Journal of surgical oncology” A woman with breast cancer developed a rare condition causing excessive fine hair growth on her face and body.
28 citations,
January 2017 in “Critical Reviews in Therapeutic Drug Carrier Systems” Nanomaterials in biomedicine can improve treatments but may have risks like toxicity, needing more safety research.
27 citations,
July 2008 in “Neuroscience” Finasteride given to baby rats causes anxiety-like behavior and worsens learning from punishment in adult rats.
26 citations,
January 2019 in “Expert Opinion on Investigational Drugs” New treatments for hair loss show promise, but more research is needed to confirm their safety and effectiveness.
26 citations,
September 2018 in “Journal of Molecular Cell Biology” Endoglin is crucial for proper hair growth cycles and stem cell activation in mice.
Oral minoxidil effectively treats hair loss, with women needing lower doses (0.25 to 2.5 mg daily) and men needing higher doses (1.25 to 5 mg daily).
17 citations,
February 2014 in “The International Journal of Neuropsychopharmacology” 16 citations,
February 2017 in “Dermatology and Therapy” The new visual scale is a quick and effective way to measure hair loss in women.
13 citations,
September 2020 in “Dermatologic Therapy” Microneedling may help hair loss, but needs more research.
13 citations,
March 2018 in “Pediatric Dermatology” Children with short anagen syndrome usually see their hair condition improve as they get older.
13 citations,
February 2015 in “Actas Dermo-Sifiliográficas” The document concludes that recognizing specific histological features of different nonscarring alopecias is crucial for accurate diagnosis and understanding hair loss progression.
11 citations,
September 2020 in “OncoTargets and Therapy” Dihydrotestosterone increases growth and spread of human brain cancer cells, and blocking its formation might help treat this cancer.
11 citations,
December 2017 in “Diabetes Therapy” Recognizing and treating early signs of insulin resistance can help prevent type 2 diabetes and improve life quality.
11 citations,
February 2016 in “Current Medicinal Chemistry” New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.
10 citations,
October 2015 in “Medicina Clínica (english Edition)” Recombinant human epidermal growth factor is versatile, effective, and safe for long-term skin and mucosal treatments.
10 citations,
September 2014 in “The Journal of Steroid Biochemistry and Molecular Biology” Allopregnanolone increases KCC2 expression in baby male rats' brains, while finasteride doesn't affect it.
9 citations,
January 2019 in “Skin appendage disorders” Researchers found a new sign of fungal infection in some patients with Seborrheic Dermatitis.
8 citations,
February 2019 in “Journal of The European Academy of Dermatology and Venereology” 8 citations,
December 2017 in “Skin appendage disorders” WNT7A gene expression is higher in early stages of androgenetic alopecia, showing the role of WNT pathway, apoptosis, and inflammation in the disorder.
8 citations,
February 1997 in “International journal of environmental analytical chemistry” Most medicinal plants in Mexican folklore have safe element levels, but arsenic exceeds safe limits in almost all.
6 citations,
April 2015 in “Behavioural Brain Research” Finasteride worsens stress effects on sensory processes, possibly linking to anxiety/depression.
6 citations,
September 2012 in “Clinical Interventions in Aging” Honokiol might help reduce male skin aging by maintaining testosterone levels.
5 citations,
January 2020 in “Skin appendage disorders” Oral dutasteride works better for hair loss, but has more sexual side effects; intralesional dutasteride is a possible alternative.
4 citations,
December 2011 in “Drug Research” Two finasteride tablet types are equally effective and can be swapped.
3 citations,
August 2016 in “Behavioural Brain Research” Finasteride given to baby rats reduces dopamine release and increases alcohol consumption in adult males.
3 citations,
February 1997 in “Annals of Plastic Surgery” The document concludes that successful hair restoration surgery should consider facial proportions and balance, and requires surgical skill, artistic judgment, and realistic goals for a natural look.
2 citations,
July 2020 in “Behavioural Brain Research” Changing neuroactive steroids in baby male rats affects their memory and learning differently as they grow up.