December 2022 in “Journal of Dermatology Research” Platelet Rich Plasma (PRP) treatment significantly improved Female Pattern Hair Loss in a study, but more trials are needed for confirmation.
5 citations,
April 2017 in “Dermatologic Surgery” PRP treatment satisfies 58% of female hair loss patients, with most noticing fuller, thicker hair and less shedding.
3 citations,
September 2018 in “Dermatologic Surgery” Platelet-Rich Plasma (PRP) can improve hair loss in cicatricial alopecia cases, but treatment must be ongoing and results vary among patients.
December 2022 in “Journal of Investigative Dermatology” This study challenges the claim that fully miniaturized vellus (V) hair follicles (HFs) in androgenetic alopecia (AGA) cannot reconvert to terminal (T) HFs, even with therapy. Using a novel humanized AGA mouse model, biopsies from 10 male AGA patients were transplanted onto SCID/beige mice, which were then treated with either 5% topical minoxidil (MXL) or intradermal platelet-rich plasma (PRP) for 4 months. Quantitative histomorphometry showed a significant decrease in V and intermediate HFs and an increase in T HFs in treated transplants compared to donor scalp skin (p<0.05, p<0.01). This suggests that V-T reconversion is possible in long-standing AGA, promoted by both MXL and PRP, although intermediate HFs may be more responsive to reconversion than fully miniaturized V HFs, highlighting the importance of early intervention in AGA management.
348 citations,
July 2017 in “Skin appendage disorders” Platelet-rich plasma shows promise for skin and hair treatments but needs more research and standardization.
70 citations,
February 2021 in “International Journal of Molecular Sciences” Fat-derived stem cells, platelet-rich plasma, and biomaterials show promise for healing chronic skin wounds and improving soft tissue with few side effects.
May 2018 in “Journal of dermatology and dermatitis” PRP is a promising treatment for autoimmune hair loss but its exact workings are not fully understood.
October 2021 in “QJM: An International Journal of Medicine” 2 citations,
August 2023 in “Journal of Cutaneous Medicine and Surgery” PRP is effective and safe for increasing hair density in people with hair loss.
July 2012 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” New treatment with Wnt proteins and growth factors safely increases hair thickness.
4 citations,
September 2020 in “PeerJ” Platelet factor 4 slows down hair growth and could make hair loss treatments more effective if removed.
39 citations,
January 2016 in “Journal of Cutaneous and Aesthetic Surgery” Injecting platelet-rich plasma during hair transplant surgery improves hair regrowth rate, speeds up skin recovery, and enhances hair quality.
8 citations,
July 2014 in “Hair transplant forum international” Bio-enhanced hair restoration, using methods like growth factors, stem cells, and ATP, results in better hair growth and density than traditional hair transplants.
7 citations,
February 2022 in “Journal of Personalized Medicine” Platelet-Rich Plasma therapy significantly increases hair density in people with Androgenic Alopecia, and works better with more treatments per month and in younger patients.
1 citations,
January 2023 in “Journal of cosmetic dermatology” Combining CO2 laser with platelet-rich plasma is more effective for treating acne scars than laser alone.
The study demonstrated that platelet-rich plasma (PRP) significantly promoted the viability and proliferation of human hair dermal papilla cells (HHDPCs) in vitro, particularly at a 5% concentration. PRP also increased the expression of alkaline phosphatase (ALP) and versican at both mRNA and protein levels. The study involved 8 healthy volunteers and used MTT assays, qRT-PCR, and Western blot analysis. These findings suggested that PRP could be a potential therapeutic tool for promoting hair follicle regeneration and treating alopecia, although further research is needed to identify the specific growth factors responsible for these effects.
76 citations,
August 2018 in “International Journal of Cosmetic Science” Dermal Papilla cells are a promising tool for evaluating hair growth treatments.
11 citations,
October 2016 in “Biomedicine & Pharmacotherapy” Both human platelet lysate and minoxidil can promote hair growth, but they affect different genes and cell survival rates.
July 2024 in “Journal of Dermatology Research Reviews & Reports” Stem cell therapy shows promise for treating hair loss by promoting hair growth.
May 2018 in “Journal of Investigative Dermatology” IL-9 increases skin cell movement but decreases their ability to invade, and this effect is controlled by cell contractility, not by MMPs.
May 2018 in “Journal of Investigative Dermatology” The conclusion is that a new method combining magnetic tweezers and traction force microscopy may help understand skin cell interactions and diseases.
May 2018 in “Journal of Investigative Dermatology” Desmoglein 3 organization in cell connections changes without calcium, affecting cell adhesion.
May 2018 in “Journal of Investigative Dermatology” Dsg1 is essential for maintaining a healthy skin barrier in mice.
May 2018 in “Journal of Investigative Dermatology” Nonmelanoma skin cancers have higher levels of certain osteopontin variants than normal skin.
June 2018 in “Advances in Cosmetic Surgery” Hair loss caused by genetics and hormones; more research needed for treatments.
November 2023 in “Applied sciences” Pig blood can be used to mass-produce stable, low-cost platelet dry powder for medical use.
34 citations,
September 2019 in “Clinical, Cosmetic and Investigational Dermatology” Light therapy can stimulate hair growth and is more effective when started early, but more research is needed on its long-term effects and optimal use.
2 citations,
November 2022 in “Journal of Biochemistry and Molecular Biology” Aging changes hair stem cells and their environment, leading to gray hair and hair thinning, but understanding these changes could help develop treatments for hair regeneration.
April 2024 in “Military Medical Research/Military medical research” Cellular and immunotherapies show promise for healing chronic wounds but need more research.