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Low-dose methotrexate is generally safe but can cause mild to severe side effects, and folic acid can reduce these risks.

Men are more likely to get infectious skin diseases, while women are more prone to autoimmune and pigment-related skin conditions, influenced by biological and environmental factors.

Volatile organic compounds can cause inflammation and increase the risk of autoimmune diseases.

Type 1 diabetes often occurs with other autoimmune diseases, and personalized treatment based on genetics can improve outcomes.

Non-biologic immunosuppressive drugs are crucial for treating autoimmune and chronic inflammatory skin diseases.

Early baldness in men may indicate risks for obesity, metabolic syndrome, insulin resistance, and heart disease, similar to women with PCOS. Alopecia areata is often linked with autoimmune diseases and mental health issues. Certain hair disorders are due to genetic issues, and chemotherapy can cause hair loss through specific biological pathways. Iron deficiency's link to hair loss is still disputed.

Breast implants are linked to autoimmune symptoms, with over half of patients feeling better after removal, but the exact cause is unclear and may involve bacterial biofilm.

The document concludes that various findings in rheumatology offer insights into disease severity, treatment responses, and potential risks in medication, with some limitations due to unspecified participant numbers.

The document concludes that managing skin conditions during pregnancy is important and requires specialized care.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

The document concludes that anti-dsDNA antibodies are not unique to SLE and their use as indicators is doubtful, highlighting the need for better understanding and classification of the disease.

SLE and DM can coexist but are rare and need careful evaluation.

COVID-19 may affect male fertility and women might have better outcomes due to hormonal and immune differences.

Auto-antibody testing is a useful but not definitive tool in diagnosing interstitial lung diseases, and using a specific algorithm could make testing more cost-effective.

PCOS causes infertility mainly due to hormonal imbalances, insulin resistance, and chronic inflammation.

Men with androgenetic alopecia, or hair loss, often have abnormal blood flow in their small blood vessels, which might be linked to inflammation and stress.

Patients need better information about the risks of long-term steroid use.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

A small forehead lesion led to the discovery of a significant brain arteriovenous malformation in a young girl.

Some vitamins and minerals like vitamin D and iron can help with certain types of hair loss, but more research is needed for others.

Skin symptoms are important for diagnosing and managing juvenile-onset systemic lupus erythematosus and usually get better with treatment.

IFN-γ and IL-2 are important for T cell activation in hair loss in mice.

The European Society of Cutaneous Lupus Erythematosus created a questionnaire to standardize patient assessment and improve care for cutaneous lupus.

Patients with Discoid Lupus Erythematosus have lower vitamin D and antioxidant levels and higher oxidative stress.

Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.

Leflunomide and methotrexate are equally effective for rheumatoid arthritis but have different side effects.

Leflunomide and methotrexate are similarly effective for rheumatoid arthritis but have different side effects.

COVID-19 may cause different types of hair loss, and the virus's effects on hair could help understand its impact on other body parts.

Some patients on immunosuppressants had a weaker immune response to the Sinovac-CoronaVac COVID-19 vaccine.

Proper periodontal treatment with xenograft effectively manages aggressive periodontitis in SLE patients.