2 citations
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January 2017 in “Journal of Pigmentary Disorders” This study explores the complex and not yet fully understood causes of premature hair greying, noting genetic factors such as Pax3 and MITE genes, potential defects in melanin transfer, and associations with certain syndromes, while stating that effective treatments are currently lacking.
1 citations
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January 2023 in “International Journal of Molecular Sciences” This review explores the role of Tregs in autoimmune skin diseases, transplantation, and skin cancer, and discusses Tregs-based therapies' potential for treating autoimmunity without reporting new experimental results.
1 citations
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July 2018 in “Elsevier eBooks” This review discusses the pathogenesis and clinical features of androgenetic alopecia, highlighting potential links to fibrosing alopecia and suggesting the need for combined therapeutic approaches; it reports no new clinical results.
1 citations
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December 2013 in “Journal of Evolution of Medical and Dental Sciences” This historical review examines the diagnostic and etiological understanding of alopecia areata, emphasizing the evolution of theories and the impact of immunological data, while providing no new clinical results.
1 citations
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February 1988 in “The BMJ” The document explains different hair and scalp conditions, including common hair loss after pregnancy or illness, drug-induced hair loss, hereditary excessive hair growth, patterned baldness, autoimmune hair loss, and permanent loss due to skin disease, with generally limited treatment options.
1 citations
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October 2025 in “International Journal of Nanomedicine” This review explores the potential for using exosomes in treating autoimmune skin diseases and promoting skin regeneration, highlighting current applications, delivery methods, and ongoing clinical trials while also identifying challenges and future research directions within dermatology.
This case report described a five-year-old girl with alopecia areata totalis who experienced significant hair regrowth after receiving dental rehabilitation for extensive untreated caries and chronic oral infection, suggesting a possible link between chronic oral infection and alopecia areata.
April 2026 in “International Journal of Drug Delivery Technology” This review highlights the various causes and treatment options for alopecia, noting that while non-scarring types often see successful hair regrowth, scarring forms require early intervention to manage inflammatory destruction of hair follicles.
January 2026 in “International Journal of All Research Education & Scientific Methods” This review highlights recent advancements in understanding and treating alopecia, emphasizing genetic and immune factors involved in different forms, and discusses emerging therapies such as gene-editing and exosome-based treatments, though achieving complete hair regrowth remains a challenge.
November 2025 in “Frontiers in Immunology” This review integrates studies on mouse models and human clinical observations to highlight the role of immune cells in skin development and how their dysregulation leads to skin disorders, suggesting potential therapeutic pathways for skin regeneration.
In this study, researchers found that CD4 T cells from the skin draining lymph nodes of mice with alopecia areata can transfer the disease to recipient mice, highlighting the key role of these cells and their interaction with CD8 T cells in the disease's development.
This review highlights new treatment options for alopecia, including JAK inhibitors and Wnt pathway-targeting therapies, which may offer better efficacy and safety than traditional treatments like minoxidil and finasteride, but notes the need for more research on long-term effects and patient-specific responses.
October 2024 in “Revista Electronica de Veterinaria” This case report suggests that Siddha medicine, using both internal and external treatments, may effectively promote hair growth in patients with Alopecia areata, based on observations of remarkable hair growth in a shorter duration.
September 2024 in “Clinical Case Reports” This case report highlights a rare presentation of APS-1 in a 28-year-old Pakistani male with cardiovascular and pulmonary symptoms, illustrating the importance of early recognition and multidisciplinary management for improved patient outcomes.
September 2024 in “Medicine” This study found that alopecia areata and asthma are linked to graft dysfunction, while primary sclerosing cholangitis presents as heterogeneous, without any pleiotropy or heterogeneity in other autoimmune diseases assessed.
March 2024 in “Research Square” This study developed a mathematical model to simulate immune interactions and hair cycle dynamics in alopecia areata, identifying influential factors affecting hair growth and offering insights into potential treatment strategies by targeting immune dysregulation.
January 2024 in “Research Square” In this study, researchers developed a mathematical model to explore how immune system dynamics affect hair follicle behavior in alopecia areata, identifying key parameters influencing disease progression and suggesting potential treatment strategies targeting immune dysregulation.
January 2024 in “Clinical and Experimental Vaccine Research” In this report, the authors describe a case where a child developed alopecia areata after receiving the fifth dose of a rabies vaccine, suggesting that the vaccine may predispose to this autoimmune hair loss by affecting immune regulation.
October 2023 in “Dermatologie pro praxi” This source outlines the autoimmune condition alopecia areata, discussing its unclear etiology, the significant psychological impact despite not being life-threatening, and the challenging nature of its treatment, which varies greatly among individuals. The article summarizes disease pathogenesis, prevention, and treatment options.
August 2023 in “Research Square (Research Square)” In this study, researchers observed that Melan A, a melanocytic marker, was significantly expressed in hair follicles of alopecia areata patients and correlated with immune infiltrates, suggesting melanocytes might contribute to the autoimmune response in this condition.
This overview discusses the condition and treatments for alopecia areata, highlighting that the JAK inhibitor baricitinib, recently approved for severe cases, shows unprecedented effectiveness but raises cost and risk debates regarding treatment of this primarily cosmetic autoimmune disorder.
March 2022 in “Research Square (Research Square)” This case report describes a 15-year-old girl with Alopecia Universalis and psychiatric conditions experiencing hair regrowth after self-medicating with cannabis, suggesting it may have therapeutic potential.
December 2021 in “Figshare” This review discusses recent advancements in targeted therapies for vitiligo, including JAK inhibitors and mesenchymal stem cells, and highlights the need for further research.
This article reviews alopecia areata as a chronic autoimmune disease affecting hair follicles and discusses its association with other autoimmune conditions, but provides no new clinical findings.
February 2021 in “Journal of pharmaceutical and biological sciences” This article reviews multiple treatments for alopecia areata, highlighting their variable efficacy and safety without any being curative; it reports no new clinical findings.
February 2020 in “Our Dermatology Online” A synthetic drug and a South American herb may help treat alopecia areata in Chinese men.
July 2025 in “International Journal of Pharmaceutical Sciences Review and Research” This case report documented a 20-year-old male with alopecia areata who experienced slight hair regrowth following treatment with cyclosporine and methylprednisolone, highlighting the importance of individualized treatment plans and consideration of medication side effects.
January 2025 in “International Journal of Dermatology Venereology and Leprosy Sciences” This review discusses the various off-label treatments for alopecia areata, highlighting that these therapies may promote hair growth but are not curative.
May 2024 in “IP International Journal of Periodontology and Implantology” This analysis reports that treating dental issues in patients with alopecia areata can improve the condition, suggesting a connection between oral infections, like periodontitis, and hair loss, alongside the roles of stress and autoimmune factors.
April 2024 in “International Journal of Research Publication and Reviews” This source highlights that alopecia areata is a complex autoimmune disorder leading to patchy, nonscarring hair loss with variable treatment responses, reflecting unmet clinical needs. Advances in genetic research are improving understanding, yet current treatments often lead to persistent relapses.