118 citations
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May 2003 in “Toxicological Sciences” Exposure to finasteride in the womb caused lasting reproductive issues in male rats.
113 citations
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October 2005 in “Journal of Investigative Dermatology” Applying a special compound can promote hair growth without harmful side effects.
109 citations
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April 2000 in “European Urology” Finasteride lowers risk of urinary issues and surgery by over 50% in 4 years.
101 citations
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April 2017 in “Nanomedicine: Nanotechnology, Biology and Medicine” Fullerenes show potential in skin care but need more safety research.
93 citations
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January 1996 in “Clinical Pharmacokinectics” Finasteride helps regrow hair and shrink prostate by reducing DHT, with some sexual side effects.
85 citations
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June 2015 in “Scientific Reports” The study found that diseases can be grouped by symptoms and that the accuracy of predicting disease-related genes varies with the data source.
81 citations
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February 2000 in “Anti-cancer drugs” Doxil showed some effectiveness against advanced prostate cancer but caused severe side effects at higher doses.
62 citations
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April 2004 in “Expert Opinion on Pharmacotherapy” Finasteride effectively treats male pattern baldness, improving hair growth and density.
59 citations
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February 2003 in “Veterinary Dermatology” Cyclosporin is effective for treating skin conditions in small animals, but requires careful dosing and monitoring for side effects.
57 citations
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January 1980 in “Journal of Cardiovascular Pharmacology” Minoxidil treats high blood pressure and side effects can be managed.
50 citations
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October 2014 in “International Journal of Clinical Pharmacology and Therapeutics” New finasteride solution effectively reduces baldness-causing hormone, potentially with fewer side effects.
48 citations
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May 2015 in “PLOS ONE” DNA variants can predict male pattern baldness, with higher risk scores increasing baldness likelihood.
45 citations
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November 2012 in “Life Sciences” Aconiti Ciliare Tuber extract may help hair grow by activating a specific cell signaling pathway.
44 citations
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August 1996 in “Drugs & Aging” Mitoxantrone is effective for treating acute leukemia, especially in older patients, with a lower risk of heart damage.
42 citations
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August 2007 in “Journal of Biological Chemistry” Most Hairless gene mutations reduce its ability to work with the Vitamin D Receptor, which might explain a certain type of hair loss.
40 citations
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April 1999 in “Drugs” Finasteride treats enlarged prostate, improves urinary flow, but may cause sexual side effects.
39 citations
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December 2018 in “Methods in molecular biology” The document concludes that computational methods using networks and various data can improve the process of finding new uses for existing drugs.
39 citations
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November 2013 in “Journal of dermatological science” Hair microRNAs could be effective biomarkers for diagnosing scleroderma.
38 citations
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March 2005 in “The journal of sexual medicine” The testosterone patch and gel are both effective, but they have different absorption patterns and effects on hormone levels.
36 citations
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November 2015 in “Forensic Science International: Genetics” Certain DNA variants can predict straight hair in Europeans but are not highly specific.
35 citations
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June 2017 in “Pharmaceutical research” Researchers developed a model that shows hair follicles increase skin absorption of caffeine by 20%.
34 citations
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May 2007 in “Neuroscience” Finasteride reduces alcohol withdrawal severity in male mice but increases it in female mice.
33 citations
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March 2009 in “European Journal of Pharmaceutical Sciences” St. John's wort increases finasteride metabolism, reducing its effectiveness; use caution when combining them.
29 citations
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January 2016 in “CNS drugs” Teriflunomide is effective and generally safe for treating relapsing-remitting multiple sclerosis.
29 citations
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July 2004 in “Pharmacology, Biochemistry and Behavior” Finasteride reduces alcohol withdrawal effects, especially in female mice.
29 citations
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October 1988 in “Journal of Steroid Biochemistry” Antiandrogens are effective for conditions like prostate cancer and skin issues, but more research is needed to confirm their benefits and minimize side effects.
28 citations
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October 2019 in “International Journal of Nanomedicine” Minoxidil nanoparticles can potentially be a more effective treatment for hair growth than current treatments.
28 citations
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December 2017 in “Lasers in Medical Science” Monochromatic light devices, especially the 308-nm excimer laser, are promising for treating alopecia areata but more research is needed.
28 citations
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February 2016 in “International Journal of Nanomedicine” Finasteride capsules with nanoparticles improve drug delivery, solubility, stability, and effectiveness.
27 citations
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April 2013 in “Reviews in endocrine and metabolic disorders” The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.