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Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

Human enzymes can detoxify harmful substances but might also increase their cancer risk.

A new gene mutation may allow some piebaldism patients to regain skin color in white patches.

New drugs targeting the JAK-STAT pathway show promise for treating inflammatory skin diseases.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Janus kinase inhibitors are promising drugs for treating autoimmune and inflammatory diseases.

Polyamines help fix DNA damage accurately in cells.

Beard and scalp hair cells have different gene expressions, which may affect beard growth characteristics.

Blocking JAK/STAT pathways can help treat hair loss from alopecia areata.

Pyrene excimer nucleic acid probes are promising for detecting biomolecules accurately with potential for biological research and drug screening.

New gene identification techniques have improved the understanding and classification of inherited hair disorders.

The document concludes that eyelash trichomegaly, which is the abnormal growth of eyelashes, can be present from birth, caused by diseases, or result from certain medications.

Changthangi goats have specific genes that help produce Pashmina wool.

A substance called TCQA could potentially darken hair by activating certain genes and increasing melanin.

Melatonin treatment increases a specific RNA in goat cells that boosts cashmere growth.

A new compound shows promise as a topical treatment for hair loss.

SA linked to mitochondrial issues and oxidative stress, while AGA involves disrupted hair growth genes.

Finding new uses for existing drugs is promising and can lead to safer, more effective medicines.

Ripretinib is effective and safe for treating advanced GIST in Chinese patients, particularly for non-gastric GISTs.

Adding soybean oil to Nonomuraea dietziae increases production of a beneficial compound by improving metabolism and enzyme systems.

No FDA-approved treatments for chemotherapy-induced hair loss existed in 2006; more research was needed.

Young women in West Bengal, India, with PCOS often have estrogen resistance, leptin receptor issues, folate deficiency, T2DM, and acanthosis, commonly linked to obesity.

Tofacitinib is a promising treatment for severe alopecia areata, with many patients experiencing complete or partial hair regrowth.

CCT128930 is a promising new drug that effectively targets and inhibits a cancer-related protein, showing potential for cancer treatment.

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

MK-2206 was safe and effectively blocked AKT signaling in cancer patients, warranting more trials.

Janus kinase inhibitors can regrow hair in alopecia areata but may cause side effects and hair loss may return if treatment stops.

Tofacitinib is a safe treatment for hair loss in children, but long-term use may be needed for best results.

Tyrosine Kinase Inhibitors are effective against cancer but can cause skin, digestive, and blood side effects, including hair loss.