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Acne is significantly influenced by genetics, and understanding its genetic basis could lead to better, targeted treatments.

People with alopecia areata often have lower vitamin D levels, which are linked to more severe and longer-lasting hair loss, but vitamin D receptor levels in the skin don't show the same pattern and don't predict treatment success.

People with Down's syndrome often have more skin problems due to a weak immune system.

iNKT cells can help prevent and treat alopecia areata by promoting hair regrowth.

Having a lot of gray hair and hair loss are linked to more severe COVID-19.

Oral tofacitinib may effectively treat hair loss in children with alopecia areata.

Thermoresponsive nanogels show promise for delivering medicine through the skin but need more safety testing and regulatory approval before clinical use.

A Japanese patient with IFAP syndrome had a severe MBTPS2 gene mutation but showed milder symptoms than previously observed cases.

Retinoids can prevent skin cancer in high-risk people but have side effects and require more research on dosing and effectiveness.

Cyclosporine A was found to increase hair growth in mouse whisker follicles.

Mice with a Gsdma3 gene mutation have thicker skin and longer hair follicle openings due to increased β-catenin levels.

Calcipotriol works almost as well as clobetasol for mild to moderate alopecia areata with fewer side effects.

Skin abnormalities can indicate immunodeficiency due to shared origins with the immune system.

The document concludes that various childhood hair and nail disorders exist, some may improve on their own, and advances in genetics and immunology could enhance treatment and counseling.

The Alopecia Areata Assessment Tool (ALTO) effectively identifies alopecia areata from other hair loss types but needs more validation.

Scientists created a 3D skin model to study a chronic skin disease and test treatments.

The document concludes that various skin conditions have specific treatments, ranging from antihistamines for urticaria to surgery and medication for tumors and chronic skin diseases.

People with alopecia areata often have thyroid autoimmunity.

Fluocinolone acetonide slows down hair follicle stem cells but speeds up skin cell growth in mice.

Afro-textured hair is more fragile and prone to certain scalp conditions, requiring careful treatment and more research for effective management.

Certain genetic variants linked to immune response increase the risk of alopecia areata in Taiwanese people.

Pangolins have lost some skin-related genes, but kept others, leading to their unique scales and skin features.

Tofacitinib may slow hair loss in scarring alopecias but is unlikely to regrow significant hair.

A genetic mutation in the LIPH gene causes tightly curled hair that stops growing in some Japanese individuals.

Tofacitinib and adalimumab are promising treatments for cicatricial alopecia with few side effects.

AP-2α and AP-2β proteins are essential for healthy adult skin and hair.

Drug repositioning offers hope for new, affordable treatments for a genetic skin disorder called ARCI.

Long-COVID has diverse, long-term health impacts, especially in young people.

A specific immune response helps control mite populations on the skin, maintaining healthy hair follicles.

More research with diverse participants is needed to determine the effectiveness of photobiomodulation devices for hair loss treatment.