86 citations,
May 2008 in “Cytokine & growth factor reviews” TNF family proteins are crucial for the development of skin features like hair, teeth, and mammary glands.
48 citations,
April 2010 in “Journal of the European Academy of Dermatology and Venereology” Men are more likely to get infectious skin diseases, while women are more prone to autoimmune and pigment-related skin conditions, influenced by biological and environmental factors.
31 citations,
May 2019 in “Nature communications” Single Blimp1+ cells can create functional sebaceous gland organoids in the lab.
21 citations,
June 2016 in “PloS one” Zebrafish need MYC and FGF to regenerate inner ear hair cells.
7 citations,
July 2011 in “Archives of Dermatology” Alopecia areata caused a boy's hair to regrow straight instead of curly, but the exact reason is unknown.
September 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Different fish use the same genes to regrow teeth.
November 2022 in “Journal of Investigative Dermatology” Scientists found a new type of skin cell that could help with skin repair and these cells work better with a certain protein.
34 citations,
June 2005 in “Developmental dynamics” Runx3 helps determine hair shape.
12 citations,
January 2009 in “Stembook” Improved understanding of stem cell mechanisms can enhance skin tissue engineering.
1 citations,
July 2023 in “Communications biology” Removing Mediator 1 from certain mouse cells causes teeth to grow hair instead of enamel.
August 2023 in “Military Medical Research” Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.
242 citations,
February 2016 in “Science” Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.
12 citations,
February 1998 in “Gene” The B2 genes are crucial for hair growth in rats.
4 citations,
January 2020 in “Cells” The research found that the gene activity in mouse skin stem cells changes significantly as they age.
2 citations,
February 2013 in “Journal of The American Academy of Dermatology” Platelet-rich plasma may improve hair density in androgenetic alopecia patients.
1 citations,
October 2023 in “European journal of histochemistry” Ozone and procaine boost the release of healing factors in platelet-rich plasma.
April 2023 in “IP Indian journal of clinical and experimental dermatology” Lichen planus is a chronic autoimmune disease that is hard to treat and more common in women.
January 2018 in “Stem cells in clinical applications” Exosomes show promise for tissue repair and regeneration with advantages over traditional cell therapies.
Cross-section trichometry is an accurate method to measure hair loss and growth.
February 2013 in “Journal of the American Academy of Dermatology” Certain gene variations might increase the risk of a hair loss condition in Koreans.
320 citations,
December 2018 in “Frontiers in Immunology” Changing how mesenchymal stromal cells are grown can improve their healing abilities.
211 citations,
November 2018 in “Nature Cell Biology” Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.
135 citations,
December 2015 in “Expert Opinion on Biological Therapy” Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.
111 citations,
January 2007 in “Seminars in cell & developmental biology” Hair, teeth, and mammary glands develop similarly at first but use different genes later.
106 citations,
November 2014 in “Cell Stem Cell” New single-cell analysis techniques are improving our understanding of stem cells and could help in treating diseases.
71 citations,
January 2015 in “The Scientific World Journal” Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.
68 citations,
December 1991 in “Annals of the New York Academy of Sciences” Hair growth can be induced by certain cells found at the base of hair follicles, and these cells may also influence hair development and regeneration.
51 citations,
November 2005 in “Journal of Medical Primatology” Alopecia in captive rhesus macaques is affected by season, sex, age, housing, and stress, with complex links between stress hormones and hair loss.
47 citations,
March 2016 in “Journal of dermatology” Understanding the genetics of rare inherited ichthyosis syndromes is key for better treatments and genetic counseling.
41 citations,
October 2008 in “The American journal of pathology” Blocking a specific protein signal can make hair grow on mouse nipples.