research Inhaled Medicines for Targeting Non-Small Cell Lung Cancer
Inhaling medicine may reduce side effects and improve treatment for a major lung cancer type.
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research The Corpus Cavernosum After Treatment With Dutasteride or Finasteride: A Histomorphometric Study in a Benign Prostatic Hyperplasia Rodent Model
Dutasteride caused more penile tissue changes than finasteride, possibly increasing erectile dysfunction risk.
research The Role of 3Rs in the Age of One Health: Where We Are and Where We’re Going
Innovative methods are reducing animal testing and improving biomedical research.
research Bisphenol-A Antagonizes the Rapidly Modulating Effect of Dihydrotestosterone on Spinogenesis and Long-Term Potentiation of Hippocampal Neurons
Bisphenol-A (BPA) increases connections between brain cells and boosts their activity, but it blocks the effects of a male hormone on brain cell plasticity.
research Perspectives of Kennedy's Disease
Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.
research Diet and Pemphigus
Avoiding certain nutrients and drugs may help manage pemphigus.
research Neurosteroids Are Endogenous Neuroprotectants in an Ex Vivo Glaucoma Model
A natural steroid in the body may protect against eye damage in glaucoma.
research Physiopathological Role of the Enzymatic Complex 5α-Reductase and 3α/β-Hydroxysteroid Oxidoreductase in the Generation of Progesterone and Testosterone Neuroactive Metabolites
The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.
research TSPO Activation Modulates the Effects of High Pressure in a Rat Ex Vivo Glaucoma Model
Activating TSPO helps protect the retina from damage caused by high eye pressure in glaucoma.
research Trepanation or Complete Removal of the Outer Table of the Calvarium for Granulation Induction: The Erbium:YAG Laser as an Alternative to the Rose Head Burr
The erbium:YAG laser is a better, safer, and faster method for scalp surgery than the traditional method.
research Culture of Pyramidal Neural Precursors, Neural Stem Cells, and Fibroblasts on Various Biomaterials
Different materials affect the growth of brain cells and fibroblasts, with matrigel being best for brain cell growth.
research ESGCT and FSGT Collaborative Congress Helsinki, Finland September 17–20, 2015 Abstracts
The congress highlighted new gene therapy techniques and cell transplantation methods for treating diseases.
research The Structure of the Cornified Claw Sheath in the Domesticated Cat (Felis Catus): Implications for the Claw-Shedding Mechanism and the Evolution of Cornified Digital End Organs
Cat claws stay sharp by shedding their outer layer through microcracks formed during activities.
research Identification and Characterization of Four Immune-Related Signatures in Keloid
Four specific genes are linked to keloid formation and could be potential treatment targets.
research Native and Engineered Extracellular Vesicles for Wound Healing
Extracellular vesicles show promise for wound healing, but more research is needed to improve their stability and production.
research The Multiple Consequences Of Obesity
Obesity leads to physical, metabolic, reproductive issues, higher healthcare costs, and mental health problems.
research Wound Treatment Using Nanomaterials
Nanomaterials like silver and gold can improve wound healing but need more research for safety.
research Weakly Supervised Learning of Biomedical Information Extraction from Curated Data
The method can effectively extract biomedical information without needing expert annotation, performing better than previous models.
research Ectoin Attenuates Cortisone-Induced Skin Issues by Suppression of GR Signaling and the UVB-Induced Overexpression of 11β-HSD1
Ectoin helps prevent cortisone-induced skin problems and supports skin health.
research Clinical Review of Ejaculatory Dysfunction
The review suggests new ways to classify ejaculation problems and recommends different treatments based on the type of issue.
research Oral Presentations: Abstracts of the Urological Society of Australia and New Zealand Annual Scientific Meeting, Melbourne, Australia
Urologists should monitor mental health in patients taking finasteride due to potential links to suicidal thoughts, adjusting dosage or stopping use if necessary. More research is needed to confirm if finasteride causes these thoughts.
research Discussion of Field Effects After Intraovarian Injection of Autologous Platelet-Rich Plasma
The document concludes that more research is needed to understand how PRP affects the ovaries and to standardize its use in treatment.
research Adipose Tissue-Derived Stromal Vascular Fraction in Regenerative Medicine: A Brief Review on Biology and Translation
Fat tissue-derived cells show promise for repairing body tissues, but more research and regulation are needed for safe use.
research Ovarian Leukocyte Distribution and Cytokine/Chemokine mRNA Expression in Follicular Fluid Cells in Women with Polycystic Ovary Syndrome
Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.
research Targeting Integrin Pathways: Mechanisms and Advances in Therapy
New therapies are being developed that target integrin pathways to treat various diseases.
research Development and Assessment of an Artificial Intelligence-Based Tool for Skin Condition Diagnosis by Primary Care Physicians and Nurse Practitioners in Teledermatology Practices
The AI tool helped primary care doctors and nurse practitioners diagnose skin conditions more accurately.
research Comparison of Artificial Sebum with Human and Hamster Sebum Samples
Artificial sebum L closely mimics human sebum for drug delivery research.
research Investigation of Drug Partition Property in Artificial Sebum
The conclusion is that measuring how drugs partition into artificial sebum is important for predicting their delivery into hair and sebaceous follicles, and it provides better information than traditional methods.
research Diffusion Properties of Model Compounds in Artificial Sebum
Different compounds move through artificial sebum at different rates, which can help choose the best ones for targeting hair follicles.
research Artificial Skin for Wound Healing
Artificial skin is improving wound healing and shows potential for treating different types of wounds.