Search

everythinglearnresearchcommunity

for

Search:↓

Mutations in the Vitamin D receptor gene can cause hair loss similar to mutations in the Hairless gene.

Women with PCOS are much more likely to experience depression.

Some COVID-19 patients have different skin problems, which might be the only sign of the virus or related to other health issues.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Solidified SEDDS improve drug stability and bioavailability better than liquid SEDDS.

PRX01, PRX44, and PRX73 are essential for root hair growth in Arabidopsis thaliana.

Cyclosporine is effective for skin conditions but has declined in use due to toxicity concerns.

The nanocrystalline suspension effectively delivers dutasteride over time with minimal inflammation.

R-spondins and their receptors help increase bone growth and may be used to treat bone loss diseases.

Retinoic acid-binding proteins in skin are regulated by β-catenin and Notch signalling.

New digital tools are improving the diagnosis and understanding of irreversible hair loss conditions.

Breast cancer treatments work better with AR activation, improving results and reducing side effects.

Androgens may influence bladder cancer progression by affecting cellular behavior.

The new anti-acne treatment HA-P5 effectively reduces acne by targeting two key receptors and avoids an enzyme that can hinder treatment.

Finasteride-treated male rats' offspring had altered glucose metabolism, potentially increasing diabetes risk.

A specific RNA molecule, circCOL1A1, affects the growth and quality of goat hair by interacting with miR-149-5p and influencing cell growth pathways.

Two new mutations in the AR gene linked to severe androgen insensitivity were found.

The Ar/miR-221/IGF-1 pathway is involved in male pattern baldness, with miR-221 potentially being a new target for treatment.

Using a certain drug on the skin can help prevent hair loss caused by pulling on the hair.

A specific pathway involving AR, miR-221, and IGF-1 plays a key role in causing common hair loss.

Phenylephrine may help prevent hair loss from pulling on the hair roots.

Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).

Higher androgen levels and site-specific AR expression cause sex-related skeletal differences, and certain steroids can boost AR expression and androgen effects in bone cells.

The nature of the side chain in RU 58841 derivatives greatly affects its AR affinity, with the N-(iodopropenyl) derivative 13 showing the highest AR binding affinity, suggesting its potential for developing high-affinity radioiodinated AR radioligands.

Male yak hair growth is influenced by DHT synthesis, which is promoted by 5α-red1 and AR during growth phases, while E2 may inhibit growth through ERα.

AI and AR are improving cosmetic dermatology but face challenges like data quality and ethical concerns.

Higher levels of heat shock protein 27 and lower levels of miR-1 can increase AR levels, leading to hair loss in men.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

ERG increases SOX9, promoting prostate cancer growth and invasion.

Blocking testosterone speeds up wound healing in males.