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Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

The more lipophilic the progesterone derivative, the better it binds to androgen receptors and has antiandrogenic effects.

Testosterone is crucial for development, growth, and various body functions in mammals.

Dexamethasone affects hair growth by altering levels of proteins that either promote or inhibit hair follicle growth.

Androgens block hair growth by disrupting cell signals; targeting GSK-3 may help treat hair loss.

Different types of androgens bind differently to two receptors, AR1 and AR2, in Atlantic croaker's brain and ovarian tissues, suggesting these receptors may control different androgen actions in fish.

Androgens prevent hair growth by changing Wnt signals in cells.

Androgens may block hair growth signals, targeting this could treat hair loss.

Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.

Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.

Certain drugs can cause early hair growth in mice by affecting the nerves.

A new compound effectively inhibits human 5α-reductase 1.

Clascoterone may be a promising treatment for hair loss.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Caffeine in cosmetics may reduce cellulite, protect skin, and stimulate hair growth, but more research is needed on its use and effects.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.

Animal models have helped understand hair loss from alopecia areata and find new treatments.

Skin has specialized touch receptors that can tell different sensations apart.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.

Finasteride affects brain and blood steroids, causing lasting sexual and emotional side effects.

The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.

Kennedy's disease leads to muscle weakness without a cure, but exercise and managing symptoms may help patients live a normal lifespan.

Targeted cancer therapies often cause skin problems that need careful management to improve patient quality of life and treatment success.