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The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

The document concludes that PCOS has a strong genetic component, but more research is needed to fully understand the specific genes involved.

Grouping certain skin cells together activates a growth pathway that helps create new hair follicles.

The HOXC13 gene affects different hair proteins in cashmere goats in varied ways and is controlled by a feedback loop and other factors.

Finasteride helps brain function in rats with liver-related brain issues.

Hair in mammals likely evolved from glandular structures, not scales.

An imbalance in gut bacteria is linked to skin immune diseases and may affect their outcomes and related health issues.

A new therapy sped up wound healing and reduced scarring in diabetic rats.

New treatments for skin conditions related to the sebaceous gland are being developed based on current research.

DHT is a strong androgen that may pose less risk to the prostate compared to testosterone.

Polygonum multiflorum extract helps hair grow longer and fights the effects of hormones that cause hair loss.

P-cadherin is important for hair growth and health, and its problems can cause hair and skin disorders.

The X5 Hairlaser might help treat male hair loss, but more research is needed.

Immune checkpoint inhibitors can cause skin issues but are linked to better cancer outcomes.

New patents show progress in developing drugs targeting the Wnt pathway for diseases like cancer and hair loss.

Gene therapy shows promise for enhancing physical traits but faces ethical, safety, and regulatory challenges.

Gamma delta T cells in the skin help with healing and defense but can also cause autoimmune issues, and more research is needed to understand how they are activated.

Thyroid hormones and androgens affect gene expression in frog reproductive organs differently between males and females.

Optimizing the structure of a specific compound greatly improved its effectiveness and precision for treating diabetic complications.

Genomic approach finds new possible treatments for hair loss.

Activating TRPV3 channels stops hair growth by killing hair follicle cells.

Retinoids can prevent skin cancer in high-risk people but have side effects and require more research on dosing and effectiveness.

XIST RNA helps regenerate hair follicles by targeting miR-424 and activating hedgehog signaling.

Some synthetic carbohydrate receptors, especially compounds 3 and 15, show strong potential for treating Zika virus.

Genetic factors affect hair loss, and molecular testing may help predict, diagnose, and treat it.

Minoxidil can cause deadly skin reaction; monitor patients closely.

Outside factors like grooming, chemicals, and the environment can damage hair and cause disorders.

The document concludes that DAB389-IL2 is promising for treating refractory cutaneous T-cell lymphoma, but more research is needed on its effectiveness and side effect management.

Short telomeres contribute to aging and cancer, and while telomerase can delay aging, it may also promote cancer.

Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.