15 citations
,
November 2024 in “Materials” This review discusses the medical and dental applications of polyhydroxyalkanoates (PHAs), highlighting their potential for improving drug delivery and providing biocompatible solutions for medical devices, but reports no new clinical results.
12 citations
,
November 2024 in “Burns & Trauma” This review highlights the critical role of neuroregulation in skin wound healing, emphasizing how neurotransmitters and neuropeptides regulate inflammation, angiogenesis, and cell proliferation, and discusses potential therapeutic strategies, such as neuromodulation, to enhance these processes.
5 citations
,
December 2021 in “Scientific Reports” In this study, researchers found that in mice, gonadal hormones and biological sex do not affect the expression of SARS-CoV-2 entry proteins ACE-2 and TMPRSS-2 in the respiratory tract, regardless of disease state.
2 citations
,
October 2025 in “Cells” This review discusses the multifunctional role of PKM2 in promoting cardiac repair and regeneration, highlighting its potential as a therapeutic target in cardiovascular medicine, but reports no new experimental results.
55 citations
,
June 2012 in “Steroids” This study found that testosterone modulates vascular cell behavior through direct actions that do not rely on its conversion to estradiol.
1036 citations
,
August 2019 in “Cells” This article provides an overview of mesenchymal stem cells, highlighting their extraction methods, differentiation potential, and applications in regenerative medicine, but reports no new clinical findings.
42 citations
,
December 2011 in “The journal of immunology/The Journal of immunology” In this study, transgenic mice with Rank expression in hair follicles showed excessive lymph node growth, which could be normalized by neutralizing the overproduced RANKL, underscoring its role in immune system regulation.
20 citations
,
September 2018 in “Bioengineering & Translational Medicine” This review discusses regenerative medicine and explores the potential of molecular imaging in enhancing personalized therapies, but it reports no new research results.
January 2026 in “Aging and Disease” This review discusses recent research on the Dickkopf protein family's involvement in non-cancerous diseases and considers their potential as biomarkers and therapeutic targets without presenting new experimental results.
April 2025 in “Journal of Diabetes & Metabolic Disorders” This study found that linc-PINT expression was significantly decreased in patients with atrial fibrillation compared to healthy controls, while several TGF-β signaling genes were increased, suggesting a potential role in heart arrhythmias' pathogenesis.
January 2024 in “Genetics in Medicine Open” In this report, two adult patients with Tatton-Brown-Rahman syndrome exhibited new cardiac features, such as atrial fibrillation and ventricular and atrial dilatation, highlighting the importance of cardiovascular follow-up in adults with this condition.
176 citations
,
June 2019 in “Cells” This review discusses dermal cell heterogeneity in wound healing and scar formation, highlighting the varied roles of different fibroblasts and the potential of skin substitutes without presenting new clinical results.
54 citations
,
October 2022 in “Cells” This review discusses the therapeutic potential of mesenchymal stem cell-derived extracellular vesicles and modern technologies like 3D bioprinting but reports no new clinical results.
46 citations
,
May 2021 in “Stem Cell Research & Therapy” This study found that strontium ranelate promotes cartilage regeneration in rats by enhancing chondrogenic differentiation of bone mesenchymal stem cells while inhibiting the Wnt/β-catenin signaling pathway.
37 citations
,
February 2024 in “Military Medical Research” In this review, biomaterial-based mechanical strategies were highlighted for their potential to enhance skin regeneration and promote scarless repair, though a comprehensive understanding of their underlying mechanisms is still needed for broader application.
31 citations
,
July 2023 in “Foods” This overview outlines the latest advancements and challenges in developing three-dimensional scaffolds for biomanufacturing cultured meat, focusing on organizing muscle stem cells to better mimic the structure of traditional meat. Results are not reported in the abstract.
19 citations
,
March 2008 in “Wound Repair and Regeneration” This article discusses the development of consensus-based guidelines for preventing lower extremity arterial insufficiency ulcers but reports no new clinical results.
18 citations
,
January 2024 in “Regenerative Biomaterials” This study developed and tested a new injectable hydrogel for chronic diabetic wounds, reporting significant improvements in wound healing through enhanced angiogenesis, epithelization, and reduction of inflammation and infection in animal models.
9 citations
,
September 2022 in “Journal of Clinical Investigation” In this study, mouse models of 22q11.2 deletion syndrome showed that growth issues in small embryonic thymuses were linked to mesenchymal cells, which could be corrected by substituting with normal mesenchyme.
5 citations
,
September 2018 in “International journal of genomics” This study found that keratin damage in mammals and birds can result from N-homocysteinylation, reducing keratin solubility and indicating significant protein modification through genetic or nutritional disruptions in homocysteine metabolism.
2 citations
,
December 2024 in “Neural Regeneration Research” This research review highlights the potential of exosome therapy to transform stroke treatment, reporting that in animal models, exosomes can reduce neuroinflammation, oxidative stress, and cell death, while promoting brain repair and regeneration. However, more evidence is needed before clinical applications in humans are established.
1 citations
,
October 2022 in “Journal of food and nutrition research” This review investigates the potential benefits of cinnamon supplementation alongside lifestyle changes for managing obesity and polycystic ovary syndrome, but it reports no new clinical results.
November 2025 in “Journal of Pharmacy and Pharmacology” This review highlights pigment epithelium-derived factor's roles in ageing and development, focusing on its antioxidant functions and support of stem cell survival, but reports no new experimental results.
106 citations
,
August 2021 in “Pharmaceuticals” This review discusses the role of extracellular vesicles in wound healing and explores their potential applications in skin repair and treatment of dermal diseases, reporting no new clinical findings.
15 citations
,
February 2015 in “Cell & tissue research/Cell and tissue research” This review examines the role of P-cadherin in skin and hair biology, emphasizing its importance in human hair growth, cycling, and pigmentation, and reports no new research findings.
This case study reports clinical improvement and complete ulcer resolution in a 29-year-old woman with ANA-negative SLE treated for segmental hyalinizing vasculitis and valvular heart disease.
39 citations
,
November 1984 in “Journal of Cardiovascular Pharmacology” Minoxidil lowers blood pressure, increases heart rate, and improves blood flow in dogs.
35 citations
,
August 1980 in “Circulation” Minoxidil may cause heart issues in animals and humans.
11 citations
,
March 2019 in “EMBO molecular medicine” This paper reviews the role of endoplasmic reticulum stress and the unfolded protein response in Hutchinson-Gilford progeria syndrome-related atherosclerosis, especially in vascular smooth muscle cells, but reports no clinical findings; intervention in these pathways is suggested as a potential therapeutic strategy.
2 citations
,
January 2019 in “Springer eBooks” The conclusion is that different blood diseases cause specific oral symptoms and require varied treatments to manage these symptoms and improve patient health.