1 citations
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September 2017 in “Journal of Investigative Dermatology” This research observed that Backhousia citriodora leaf extract effectively reduced sebum production and improved sebum composition across different ethnicities, significantly decreasing skin oiliness and the likelihood of shiny skin when used in a cream applied twice daily for 28 days.
This study found that human hair follicle cells suppress immune activity, with somatostatin playing a significant role, suggesting potential applications for treating inflammatory hair loss conditions.
July 2025 in “Journal of Investigative Dermatology” TRIV-509 quickly improves skin barrier and cell health in atopic dermatitis.
April 2026 in “Proceedings of the National Academy of Sciences” In this study, Tmem30b was identified as a key regulator of outer hair cell structure in mice, and its modulation may offer a therapeutic approach for certain types of hearing loss.
21 citations
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October 2017 in “Cell death and disease” This study found that the absence of the stress-responsive protein Sesn2 increased hair cell susceptibility to gentamicin in the inner ear, indicating Sesn2's potential protective role against aminoglycoside-induced damage.
5 citations
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April 2024 in “Science China Materials” 1 citations
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October 2021 in “Journal of Investigative Dermatology” 2 citations
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April 2016 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found that a novel saw palmetto supercritical CO2 extract effectively inhibits 5α-reductase type II in vitro, suggesting its potential for promoting prostate health in benign prostatic hyperplasia.
October 2009 in “The American Journal of Gastroenterology” This case report suggests that isolated amylase deficiency can lead to failure to thrive in children, and pancreatic enzyme supplementation may improve associated symptoms.
70 citations
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August 2006 in “Cancer Research” This study found that inhibiting AP-1 activity in mice modified tumor development, leading to transdifferentiation between squamous and sebaceous tumors, with molecular analysis suggesting AP-1's role in maintaining tumor cell identity.
April 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This case report proposes that Post-Finasteride Syndrome might be sustained by specific microbes in the small intestine affecting hormone excretion and mitochondrial function, warranting further investigation in a larger cohort.
2 citations
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October 2025 in “Antimicrobial Agents and Chemotherapy” This study found that cepharanthine may be a promising treatment for enterovirus infections, as it offered full protection to mice against lethal EV71 challenges and reduced viral titers and pathology.
December 2025 in “Bioengineering” This review explains that dysregulated sebum secretion and composition contribute to acne and impaired skin barriers while highlighting factors like diet and hormones affecting sebaceous activity, and identifies novel molecular targets and model systems for future therapeutic developments.
46 citations
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April 2008 in “Archives of Dermatological Research” This study found that substance P may be involved in the pathogenesis of acne by increasing the expression of certain cytokines and receptors in cultured sebocytes.
63 citations
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November 2009 in “British journal of dermatology/British journal of dermatology, Supplement” This study found that the subtilisin protease Sub3 from Microsporum canis is essential for adherence to the feline epidermis but is not necessary for invading epidermal structures.
24 citations
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March 2022 in “Stem Cell Research & Therapy” This study found that dendritic epidermal T cells and their exosomes enhance epidermal stem cell proliferation, accelerating wound re-epithelialization in the skin.
1 citations
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October 2023 in “PROTOPLASMA”
3 citations
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May 2018 in “Reproductive Sciences” In this randomized study, BAY 1158061, a prolactin receptor antibody, was found to be safe, well-tolerated, and exhibited low immunogenicity in healthy postmenopausal women, but had no effect on serum prolactin levels compared to placebo.
2 citations
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September 2024 in “Asian Journal of Pharmaceutics” This research discusses advancements in niosomal drug delivery systems, highlighting their promising potential to improve targeted drug delivery due to their ability to encapsulate various drug types efficiently, offering advantages over traditional liposome systems in terms of chemical stability and therapeutic efficacy.
23 citations
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August 2018 in “Biochimica and biophysica acta. Molecular and cell biology of lipids” This article reviews the roles of lesser-known secreted phospholipase A2 isoforms in various biological processes, such as immune suppression, metabolic regulation, epidermal hyperplasia, and male reproduction, without reporting new clinical findings.
4 citations
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October 2022 in “Microbial Cell Factories” This study identified novel endophytic actinobacteria from the Citrullus colocynthis plant with antibacterial properties, suggesting potential for new antibiotic development against multi-drug-resistant bacteria.
48 citations
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March 2010 in “PloS one” This study found that the co-ablation of C/EBPalpha and C/EBPbeta in adult mouse skin disrupted sebocyte differentiation and epidermal homeostasis, highlighting their critical roles in these processes.
3 citations
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August 2022 in “Pharmaceuticals” This study observed that a self-emulsifying drug delivery system for finasteride significantly enhanced bioavailability in rats compared to commercial tablets, but the formulation was found to be thermodynamically unstable.
13 citations
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November 2005 in “Epilepsia” This study suggests that the anticonvulsant effects of deoxycorticosterone in young rats may be mediated by its metabolites and interactions with multiple receptors, including mineralocorticoid and progesterone receptors.
This review describes deep eutectic solvents as a green alternative to toxic solvents in extracting bioactive compounds, highlighting their sustainability, production from natural ingredients, and beneficial properties for pharmaceutical applications.
2 citations
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March 2013 in “BMJ Case Reports” In this case study, zinc deficiency persisted despite supplementation in a patient with severe malnutrition and empyema, potentially due to nutrient absorption competition and proton pump inhibitor use.
8 citations
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February 2022 in “Molecules” This study found that Asparagus racemosus root extract significantly reduced facial sebum production and pore size in male volunteers, suggesting potential application as an anti-sebum ingredient in cosmetics.
13 citations
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January 2002 in “Biochemical and biophysical research communications” This study observed that interferon β secreted by dermal papilla cells may negatively regulate the growth of outer root sheath cells in hair follicles.
147 citations
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August 2005 in “The Plant Cell” This study identified a key Arabidopsis thaliana gene, TIP1, whose product is involved in S-acylation crucial for normal plant cell growth, particularly affecting root hair development.
June 2022 in “Pflügers Archiv - European Journal of Physiology” This study found that the deletion of soluble epoxide hydrolase (sEH) in mice altered the hair follicle cycle and increased hair growth through effects on hair follicle stem and matrix cells.