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Histone demethylases play a key role in the development of many diseases and may be targets for treatment.

AP-2α and AP-2β proteins are essential for healthy adult skin and hair.

Certain genes are linked to the quality of cashmere in goats.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.

When skin blisters, healing the wound is more important than growing hair, and certain stem cells mainly fix the blisters without helping hair growth.

Foxn1 gene regulation is crucial for thymus development but not for hair growth.

Keratin gene expression helps understand different types of skin cells and their development, and should be used carefully as biological markers.

Bioassays help find useful compounds in nature for making medicines, supplements, and cosmetics.

UK medical students lack dermatology education, liver biopsy patients with risk factors show more fibrosis, and certain fungi resist drugs due to melanin; genetics may influence female hair loss.

Eicosanoids are crucial for skin health, and targeting their pathways may help treat skin conditions.

Mutations in certain receptors can cause diseases and offer new treatment options.

A boy with a rare skin condition and kidney disease improved with cyclosporine after steroids failed, suggesting a new treatment approach.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

Androgen receptors in the mouse brain may explain cognitive and mood changes in prostate cancer treatment.

Urologists should monitor mental health in patients taking finasteride due to potential links to suicidal thoughts, adjusting dosage or stopping use if necessary. More research is needed to confirm if finasteride causes these thoughts.

ΔNp63α stops TAp73β from working in skin cancer by blocking its access to specific genes, not by directly interacting with it.

Nanostructured delivery systems could potentially improve hair loss treatment by targeting drugs to hair follicles, reducing side effects and dosage, but the best size, charge, and materials for these systems need further investigation.

Vav2 and Vav3 proteins help control skin stem cell numbers and activity in both healthy and cancerous cells.

Choosing the right method to separate skin layers is key for good skin cell research.

Different small areas within hair follicles send specific signals that control what type of cells stem cells become.

Nanocarriers could improve how drugs are delivered through the skin but require more research to overcome challenges and ensure safety.

New drugs for heart disease may be developed from molecules secreted by stem cells.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

Using radiation to make mice's hair turn gray helps study and find ways to prevent or reverse hair graying.

Researchers identified genes and proteins that may influence wool thickness in sheep.

A mutation in the KRT71 gene causes a hair disorder by disrupting hair follicle structure and texture.

Skin-derived stem cells grow faster and are easier to obtain than hair follicle stem cells, but both can become various cell types.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.