January 2024 in “Wiadomości Lekarskie” This study highlights the potential of cosmetic products combining fibroblast growth factors and antioxidants like thioproline, ergothioneine, silymarin, and rosmarinic acid, to mitigate skin aging by reducing oxidative stress and enhancing cellular protection in the skin.
November 2023 in “South African journal of botany” This study found that Eclipta alba (L.) cultivated in France exhibited significant anti-inflammatory, antioxidant, and anti-collagenase activities, attributed mainly to compounds like wedelolactone and demethylwedelolactone, suggesting potential use as an anti-aging cosmetic ingredient.
August 2023 in “Theoretical and Natural Science” This review discusses the potential anti-aging effects of adipose-derived stem cells on facial skin, such as reducing wrinkles, whitening skin, and promoting hair growth, but provides no new clinical results.
July 2023 in “International Journal of Molecular Sciences” This study found that N,N-dimethylglycine sodium salt promoted proliferation and migration of cultured human epidermal keratinocytes and had anti-inflammatory and antioxidant effects in vitro.
April 2023 in “Journal of Investigative Dermatology” This report details the development of a PSR™ Terminalia extract with antioxidant and anti-aging potential, highlighting its rich composition in phenolic acids, polysaccharides, and organic acids, without new clinical results.
September 2022 in “The Korean Tea Society” This study identified several active compounds in Houttuynia cordata and found that most demonstrated significant antioxidant and acetylcholinesterase inhibitory activity, potentially useful for developing functional tea products.
May 2018 in “International journal of cell science & molecular biology” This article discusses the biology of cosmetic aging and the chemical pathways involved, emphasizing research advancements that aid clinicians in rejuvenating skin and increasing scalp hair density, but it provides no new results.
September 2017 in “Journal of Investigative Dermatology” In this study, the authors found that a botanical extract with anti-inflammatory and anti-oxidative properties stabilized hair loss and preserved natural hair pigmentation and strength over six months.
In this study, subcutaneous injection of mesenchymal stem cell-conditioned medium promoted regeneration of mice skin aged by D-galactose, improving skin thickness, vascularization, and collagen density.
November 2016 in “Universiti Putra Malaysia Institutional Repository (Universiti Putra Malaysia)” This study found that Dendrobium sabin flower extracts, especially the methanolic one, demonstrated strong antioxidant and anti-aging properties without significant toxicity, suggesting its potential in treating photo-induced skin aging.
August 2010 in “Acupuncture & Electro-Therapeutics Research” In this study, using far-infrared oily cream for massage therapy was associated with increased normal cell telomere length and improvements in stress-induced hair and skin conditions.
January 2008 in “Journal für Kardiologie (Krause & Pachernegg GmbH)” Healthy aging can be promoted through physical activity, lifestyle changes, and certain treatments.
74 citations
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January 2014 in “Journal of Investigative Dermatology” High kallistatin levels in diabetics worsen wound healing by blocking important cell signals.
January 2025 in “Open Medicine” This study found that high-concentration cell-free adipose extract effectively reduced collagen deposition and blood vessel formation in a rabbit ear model, showing promise for preventing and treating hypertrophic scars.
November 2025 in “Plant Science Today” This review explores the potential benefits of natural plant-based products for skin anti-aging, assessing effects on wrinkles, oxidative stress, pigmentation, and hydration, while also underscoring the importance of lifestyle factors such as diet, exercise, and sleep in skin health maintenance.
10 citations
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October 2018 in “Journal of molecular and cellular cardiology/Journal of Molecular and Cellular Cardiology” This study identified NM_026333 as a potential anti-aging gene that, when induced, may alleviate proton-induced aging symptoms in CF6-overexpressing and high salt-fed mice.
4 citations
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April 2018 in “Journal of Investigative Dermatology” This study suggests that hydroxypinacolone retinoate (HPR) may be an effective alternative to tretinoin for anti-aging skin treatments, offering similar collagen production benefits without increased skin irritation.
1 citations
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September 2023 This study's overview highlights that lifestyle factors like nutrition, sleep, physical activity, and social interactions can significantly enhance skin health with aging. The authors suggest social media campaigns promoting these habits could potentially improve skin well-being in the future.
June 2026 in “International Journal on Science and Technology” This source redefines anti-aging medicine as "precision healthspan pharmacology," suggesting that rather than just treating diseases or accepting aging, pharmacology should focus on expanding functional capacity across various health domains, while emphasizing the importance of fundamental physiological and psychosocial health factors.
April 2023 in “Journal of Investigative Dermatology” HA-iMSC-EVs can improve skin aging by boosting cell growth and restoring collagen and elastin.
October 2022 in “Zenodo (CERN European Organization for Nuclear Research)” This source describes Kudo Anti-Aging Gummies, which are promoted as a natural supplement designed to reduce wrinkles, enhance hair and nail health, and improve skin appearance by restoring collagen, with results purportedly visible within 1-2 months.
April 2016 in “Journal of Investigative Dermatology” This study found that gypenosides from Gynostemma pentaphyllum increased procollagen synthesis in vitro and reduced periorbital wrinkles by about 14% in a clinical trial with 24 women.
April 2011 in “한국생물공학회 학술대회” This study found that an anti-atopic lotion containing fucoidan helped heal skin damage in hairless mice with atopic dermatitis by reducing skin thickness and modulating immune responses.
33 citations
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January 2022 in “Scientific Reports” This study found that loading CoQ10 into a protransfersomal emulgel improved its stability and anti-ageing effects in UV radiation skin-aged induced-mice, without causing skin irritation.
21 citations
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November 2023 in “International Journal of Molecular Sciences” This ex vivo study reported that melatonin significantly improved certain aging biomarkers in aged human skin, including reduced mTORC1 activity, increased fibrillin-1, and enhanced collagen and elastic fiber organization, though other key biomarkers remained unchanged.
18 citations
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January 2017 in “Dermatologic Surgery” This review examines intrinsic and extrinsic aging impacts and presents evidence-based lifestyle recommendations to complement cosmetic procedures for enhanced antiaging outcomes, but it reports no new clinical results.
3 citations
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May 2021 in “Evidence-based Complementary and Alternative Medicine” This review discusses the potential antiaging effects of Chinese herbal medicines and suggests their role in regulating aging-related genes through various signaling pathways; it reports no new clinical results.
December 2025 in “International Journal of Molecular Sciences” In this study, O. forskahlii seed oil was found to promote hair growth in rats and exhibit anti-aging effects on human skin cells by enhancing fibroblast proliferation and inhibiting inflammation and enzyme activity, indicating potential for cosmetic use.
July 2014 in “Planta Medica” This article reviews the use of Eclipta Alba, a traditional Ayurvedic herb, in liver health, hair growth, and diabetes management, but it reports no new research findings.
50 citations
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April 2018 in “Cosmetics” This study found that a topical gel formulation containing rice water demonstrated in vitro antioxidant activity and elastase inhibition, suggesting its potential as an anti-aging skincare ingredient.