research Regulation of Masculinization: Androgen Signaling for External Genitalia Development
Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.
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research Tumor Mapping in Two Large Multigenerational Families With CYLD Mutations
CYLD mutations cause a variety of skin tumors with symptoms starting around age 16, and treatments are currently limited.
research A Practical Approach to the Diagnosis and Management of Hair Loss in Children and Adolescents
Early and personalized treatment for hair loss in young people is crucial to prevent permanent damage and should include psychological support.
research Acquired Scalp Alopecia: A Review
Early diagnosis and treatment are crucial for preventing permanent hair loss in various scalp conditions, and while new treatments are promising, more research is needed to evaluate their effectiveness.
research Azasteroids as Inhibitors of Testosterone 5α-Reductase in Mammalian Skin
Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.
research Steroidogenic Isoenzymes in Human Hair and Their Potential Role in Androgenetic Alopecia
Steroidogenic isoenzymes may help improve treatments for common hair loss.
research The Hair Follicle: An Underutilized Source of Cells and Materials for Regenerative Medicine
Hair follicles are valuable for regenerative medicine and wound healing.
research Genetic Variants Associated with Hyperandrogenemia in PCOS Pathophysiology
Certain genetic variations are linked to increased androgen levels in PCOS, but more research is needed to understand these connections fully.
research The Use of Photodynamic Therapy for Treatment of Acne Vulgaris
Photodynamic Therapy is an effective treatment for mild to severe acne.
research Non-Canonical Dimerization of the Androgen Receptor and Other Nuclear Receptors: Implications for Human Disease
Mutations in certain receptors can cause diseases and offer new treatment options.
research Dermatologic Conditions in Transgender Populations
Transgender patients need proper skin care, especially when undergoing hormone treatments, to manage issues like acne and hair loss.
research Androgenetic Alopecia: Combing the Hair Follicle Signaling Pathways for New Therapeutic Targets and More Effective Treatment Options
New treatments for hair loss may target specific pathways and generate new hair follicles.
research Non-Psoralen Treatment of Vitiligo. Part II. Less Commonly Used and Experimental Therapies
Some alternative vitiligo treatments show promise, but none are as effective as psoralens and UVA.
research Polycystic Ovary Syndrome in Adolescents
The document concludes that diagnosing PCOS in teenagers is difficult and should focus on specific hormone levels and menstrual irregularities, while also considering treatment for symptoms and related health issues.
research The Utility of Metformin Therapy in Reproductive-Aged Women with Polycystic Ovary Syndrome
Metformin helps regulate menstrual cycles, induce ovulation, and improve pregnancy outcomes in women with PCOS.
research Congenital Adrenal Hyperplasia: A Detailed Review of 21-Hydroxylase Deficiency
CAH is a genetic disorder affecting cortisol production and causing hormonal imbalances, with treatment and diagnosis varying by form and symptoms.
research Gynecologic and Andrologic Dermatology and the Metabolic Syndrome
Skin diseases linked to insulin resistance should be managed to prevent diabetes and reduce heart disease risk.
research Common Dermatologic Conditions
The document concludes that quick referral and appropriate treatments are crucial for managing common skin conditions and preventing permanent damage.
research Metabolic Syndrome: A New Definition and Management Guidelines
New guidelines stress early diagnosis and lifestyle changes to manage metabolic syndrome and prevent complications.
research Finasteride
Finasteride reduces prostate cancer risk but may increase high-grade cancer chances.
research The Biology of Hair Growth
Hair growth is influenced by hormones and goes through different phases; androgens can both promote and inhibit hair growth depending on the body area.
research Outperforming Ourselves: Invitation for Dialogue
The critique suggests that Wilton's work unintentionally supports the very stereotypes it aims to question and calls for a broader, more inclusive approach to understanding gender.
research Progestogens in Menopausal Hormone Therapy
Progestogens are essential in menopausal hormone therapy to prevent uterine cancer and must be chosen carefully based on individual needs.
research COVID-19 Pandemic: What About the Gonads?
COVID-19 may affect male fertility and women might have better outcomes due to hormonal and immune differences.
research Androgens and Hair: A Biological Paradox with Clinical Consequences
Androgens can both increase body hair and cause scalp hair loss.
research Potential Factors Contributing to Androgenetic Alopecia
Male pattern baldness may be caused by factors like poor blood circulation, scalp tension, stress, and hormonal imbalances, but the exact causes are still unclear.
research Immunohistochemical Patterns in the Interfollicular Caucasian Scalps: Influences of Age, Gender, and Alopecia
Age, gender, and hair loss affect scalp characteristics differently in young Caucasian adults.
research 11α-Hydroxyprogesterone, a Potent 11β-Hydroxysteroid Dehydrogenase Inhibitor, Is Metabolized by Steroid-5α-Reductase and Cytochrome P450 17α-Hydroxylase/17,20-Lyase to Produce C11α-Derivatives of 21-Deoxycortisol and 11-Hydroxyandrostenedione In Vitro
11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.
research Androgen Effects in Mammals
Testosterone is crucial for development, growth, and various body functions in mammals.
research Structure and Function of the Skin
The skin has multiple layers and cells, serves as a protective barrier, helps regulate temperature, enables sensation, affects appearance, and is involved in vitamin D synthesis.