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Mutations in the androgen receptor gene cause Androgen Insensitivity Syndrome, affecting sexual development.

Women with androgenetic alopecia experience worse physical well-being and quality of life, but similar mental health compared to those without it.

Selenium might help with insulin resistance and cholesterol in PCOS, but more research is needed to confirm its benefits.

Finasteride exposure affects gene expression and anogenital distance in male rat fetuses.

Possible link between androgens and COVID-19 severity; more research needed.

People with Myotonic Dystrophy type 1 are more likely to have certain skin conditions, but not more likely to get skin cancer.

Hormone imbalance is linked to Hidradenitis Suppurativa, a skin condition, and treatments like anti-androgenic therapy and metformin can help. It's also suggested to check patients for insulin resistance and Polycystic Ovary Syndrome.

Spironolactone might lower the chance of getting rosacea.

ADAM 10 and ADAM 12 proteins are involved in different stages of hair growth and could be targets for treating hair disorders.

Phytoconstituents from Cyperus Rotundus may help treat hirsutism by interacting with the 5 α reductase enzyme.

Acne can appear or persist in adulthood due to hormonal changes, external factors, or substance use, and requires appropriate treatment.

Athletes need effective management of skin disorders for their performance and well-being.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

Eating a lot of soy might lower the chance of early hair loss in men likely to get it.

PRP shows promise but lacks consistent evidence and regulation.

Melatonin, usually known for sleep regulation, also has antioxidant properties that can protect skin, stimulate hair growth, and improve skin conditions, with topical application being more effective than oral use.

Women's ovarian hormones and adrenal androgens change throughout life, affecting hair loss and health.

Dermal papilla cells are key for hair growth and could help us understand and treat hair loss.

Wnt10b overexpression can regenerate hair follicles, possibly helping treat hair loss and alopecia.

Certain immune system proteins are important for skin healing but can cause problems if there are too many of them.

The document concludes that treating PCOS requires a combination of drugs to manage reproductive and metabolic symptoms, with more research needed on combination therapies.

Different stem cells are key for hair growth and health, and understanding their regulation could help treat hair loss.

The UK Intellectual Property Office allows granting of supplementary protection certificates with negative terms.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

Androgens have complex effects on hair growth, promoting it in some areas but causing hair loss in others, and our understanding of this is still evolving.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

Spironolactone effectively reduces hair growth in women with hirsutism and is generally well-tolerated.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.