18 citations,
March 2015 in “Journal of Endocrinological Investigation” The research suggests that the ZP4 gene is linked to egg development in women with PCOS but requires more study to understand its role in infertility.
1 citations,
May 2009 in “Wiley-Blackwell eBooks” Early treatment of PCOS in teens is crucial to prevent long-term health issues like diabetes and heart disease.
4025 citations,
December 2003 in “Human Reproduction” The 2003 consensus updated PCOS diagnosis criteria and linked PCOS to higher risks of diabetes and heart problems, recommending lifestyle changes to lower these risks.
249 citations,
November 2003 in “Clinical endocrinology” Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.
28 citations,
August 2009 in “Nursing for Women's Health” Cognitive behavioral strategies help women with PCOS make lifestyle changes to improve their health.
28 citations,
November 2007 in “Medical Clinics of North America” Obesity worsens Polycystic Ovary Syndrome symptoms, and weight loss is a key treatment.
24 citations,
March 2010 in “Value in Health” The PCOS-specific questionnaire needs more work to fully measure quality of life in clinical trials.
21 citations,
September 2017 in “Journal of Obstetrics and Gynaecology Research” Chromium supplements don't improve insulin, hormone levels, or cholesterol in women with PCOS but raise testosterone levels.
21 citations,
June 2016 in “Reproductive Sciences” Women with PCOS, especially those overweight, have higher levels of IL-18 in their endometrium, which may affect fertility.
19 citations,
June 2016 in “Gynecological Endocrinology” Women with PCOS often have more sleep problems than the general population.
19 citations,
July 2013 in “The obstetrician & gynaecologist” The document concludes that careful evaluation is needed to diagnose PCOS correctly due to similar symptoms in other conditions, and accurate testosterone level measurement is crucial.
17 citations,
May 2019 in “Diabetes and Metabolic Syndrome: Clinical Research and Reviews” High fasting insulin levels in women with PCOS are linked to a higher risk of heart and metabolic problems.
14 citations,
January 2018 in “Endocrinology and Metabolism” Many infertile women with PCOS in Central Vietnam have metabolic or insulin resistance syndrome, with obesity and older age increasing the risk.
11 citations,
July 2007 in “Journal of Hepatology” Women with PCOS often have liver disease, so liver health checks are important for them.
6 citations,
August 2018 in “BMJ open sport and exercise medicine” Resistance training might help with PCOS symptoms, but more research is needed.
3 citations,
April 2019 in “Journal of psychosexual health” Women with PCOS often have sexual problems, and treating these issues early can improve satisfaction and reduce healthcare costs.
2 citations,
June 2009 in “The Nurse practitioner” Doctors should recognize and treat PCOS early in primary care to manage symptoms and lower risk of other health issues.
1 citations,
February 2018 in “InTech eBooks” PCOS in lean women is a serious health condition with implications beyond fertility, affecting metabolism and increasing cardiovascular disease risk.
PCOS has a strong genetic basis, but more research is needed to fully understand it.
October 2024 in “South Eastern European Journal of Public Health” A 3-month treatment improved PCOS symptoms and reduced certain immune proteins.
May 2023 in “International Journal of Home Science” PCOS is linked to metabolic issues and infertility, needing more research.
September 2018 in “Fertility and Sterility” High levels of testosterone and anti-Müllerian hormone before pregnancy are linked to a higher risk of newborns needing intensive care.
August 2015 in “Evidence Based Women Health Journal (Online)” Inositol was more effective than Metformin in treating symptoms of PCOS in women.
February 2012 in “InTech eBooks” PCOS increases the risk of heart disease and type 2 diabetes in women.
June 2008 in “CRC Press eBooks” PCOS may have evolved as an advantage in past environments with food scarcity.
343 citations,
December 2008 in “Endocrine Reviews” Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.
169 citations,
August 2004 in “Baillière's best practice & research. Clinical obstetrics & gynaecology/Baillière's best practice and research in clinical obstetrics and gynaecology” Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.
167 citations,
January 2006 in “Gynecological Endocrinology” Women with PCOS have lower quality of life, especially in mental health and energy, and managing weight can help improve it.
116 citations,
December 2013 in “European journal of endocrinology” Combining liraglutide and metformin helps obese women with PCOS who didn't lose weight on metformin alone to lose more weight.
111 citations,
November 2010 in “Human Reproduction” South Asian women with PCOS are more likely to have metabolic issues and central obesity, and simple measures like waist size and blood pressure can help identify these risks early.