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Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Hormones and genetics affect hair growth and patterns, with some changes reversible and others not.

Insulin resistance contributes to hormone imbalances in many women with polycystic ovary syndrome.

Both drugs lower DHT levels, with GI198745 being more effective.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.

The document concludes that understanding hair follicles requires more research using computational methods and an integrative approach, considering the current limitations in hair treatment products.

The spiny mouse is a unique menstruating rodent that can help us understand menstruation and reproductive disorders.

Sargassum muticum extract and its component apo-9'-fucoxanthinone may help hair growth and treat hair loss.

The study created a test that found hormonal and toxic effects in plant and fungal extracts using prostate cancer cells.

Green tea component EGCG may help prevent hair loss by changing microRNA levels in certain scalp cells.

SARS-CoV-2, the virus causing COVID-19, can affect all endocrine organs and systems, altering their function and potentially leading to disorders. Factors like diabetes and obesity increase infection risk and severity. Understanding these effects is key for effective treatment.

Nanog gene boosts stem cells, helps hair growth, and may treat hair loss.

Researchers made a cell line that grows quickly and can help with hair growth research.

Dihydrotestosterone increases growth and spread of human brain cancer cells, and blocking its formation might help treat this cancer.

Irregular menstrual cycles in exercising women may be linked to energy deficiency or hormonal imbalances, requiring careful diagnosis for proper treatment.

The conclusion is that standardizing testosterone measurement methods is essential for better diagnosis accuracy in women.

Progestogens are essential in menopausal hormone therapy to prevent uterine cancer and must be chosen carefully based on individual needs.

The paper suggests that hair loss might be caused by skull growth, not just DHT's effect on hair follicles, and calls for more research.

Cytochrome P-450 enzymes in the skin help break down various substances and could be targeted to treat skin conditions.

Synthetic ceramides may help hair growth by boosting cell growth in hair follicles.

Sardinians were historically short due to a mix of genetics and factors like disease and poor nutrition, but recent height increases suggest better living conditions had a bigger impact.

Hair follicles and deer antlers regenerate similarly through stem cells and are influenced by hormones and growth factors.

Melatonin receptors, found in many body parts, can help treat various diseases like depression and diabetes due to their effects on inflammation, tumor progression, sleep disorders, and body mass regulation.

MendelVar is a tool that helps identify important genes by combining GWAS data with Mendelian disease information.

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

Father's finasteride use may affect son's fertility and testicular function.

The document concludes that protecting skin from the sun, avoiding smoking, and using treatments like Minoxidil and Finasteride can help manage skin and hair aging.

ADAM17 could be a potential target for treating PCOS.