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Male-pattern hair loss is largely influenced by genetics, with key genes identified.

Testosterone is crucial for development, growth, and various body functions in mammals.

Androgens may block hair growth signals, targeting this could treat hair loss.

Aromatase gene variation may increase female hair loss risk.

Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

The document concludes that hair transplantation and gene therapy may be important for future hair loss treatment.

The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.

Certain drugs change freshwater snail shells to a "banana" shape.

Testosterone may slow down wound healing and increase inflammation.

TR3 is mainly found in hair follicle stem cells and may be involved in hair loss.

Beta-caryophyllene, found in essential oils, helps wounds heal better in multiple ways.

SARS-CoV-2, the virus causing COVID-19, can affect all endocrine organs and systems, altering their function and potentially leading to disorders. Factors like diabetes and obesity increase infection risk and severity. Understanding these effects is key for effective treatment.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

Molecular diagnostics help identify genetic defects causing endocrine diseases, improving diagnosis and treatment options.

PCOS is a complex condition with major health impacts, needing more research for better diagnosis and treatment.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Androgenetic alopecia involves genetics, hormones, and can be treated with medications or surgery.

Researchers found 71 genetic regions linked to male pattern baldness, which account for 38% of its genetic risk.

Women generally handle heart enlargement better than men, but it's riskier for them if it occurs; hormones like estrogen offer some protection.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

Finasteride has a higher risk of reproductive side effects than minoxidil.

Found different proteins in balding and non-balding cells, giving insight into hair loss causes.

Men using hair loss drugs like finasteride may experience sexual side effects like erectile dysfunction, but it's unclear who will be affected and when. Treating depression and sexual symptoms is suggested, as these men often have higher rates of both. More research is needed to understand why these side effects occur.

Androgens can both increase body hair and cause scalp hair loss.

Bald men may have a lower risk of testicular cancer.

Androgens play a key role in hair growth and disorders like baldness and excessive hairiness.

Female pattern hair loss involves thinning hair on crown and frontal scalp, diagnosed by hair ratio, and treated with minoxidil, antiandrogens, or hair transplantation.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.