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Sex hormones may affect COVID-19 severity, with estrogen possibly reducing risk and testosterone potentially increasing it.

Sex steroids, especially progesterone, can slow down the growth of mouse melanoma cells.

Testosterone is crucial for development, growth, and various body functions in mammals.

Using two drugs together, Flutamide and 4-MA, is more effective for blocking male hormones than using each one alone.

Androgens may block hair growth signals, targeting this could treat hair loss.

Hormonal treatments can help with hair loss, acne, and excess hair growth, but it takes 3-6 months to see results and patients should know the possible side effects.

Polygonum multiflorum extract helps hair grow longer and fights the effects of hormones that cause hair loss.

The T-zone on the face has more androgen receptors and produces more oil than the U-zone.

Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.

Flutamide and finasteride reduced sex hormones in pregnant hyenas, but increased them in males.

Dexamethasone affects hair growth by altering levels of proteins that either promote or inhibit hair follicle growth.

Gene mutations can cause problems in male genital development.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

Androgens prevent hair growth by changing Wnt signals in cells.

Androgen Deprivation Therapy for prostate cancer often reduces sexual function but intermittent therapy may be more tolerable.

Blocking the FGF5 gene in sheep leads to more fine wool and active hair follicles due to changes in certain cell signaling pathways.

High levels of male hormones in pregnant mice cause heart enlargement and poor heart function in their female babies.

Antiandrogen drugs can reduce PSA levels in women with excess hair, suggesting PSA is a sign of male hormone activity in women.

MENT could be a better option than testosterone for male hormone therapy and birth control because it works well at lower doses and has fewer side effects on the prostate.

A protein called ectodysplasin-A2 increases a hair growth inhibitor in balding cells, which could be a target for hair loss treatment.

High androgen levels can cause excessive hair growth and may indicate serious health issues, including heart disease and fertility problems.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Estrogens and SERMs can help with skin aging, but their safety and effectiveness need more research.

SHBG binding properties are unchanged in male liver cirrhosis patients.

FGF9 controls which receptors it binds to through a process where two FGF9 molecules join, and changes in FGF9 can lead to incorrect receptor activation.

PTHRP agonists can stimulate hair growth, especially in damaged follicles, while antagonists may initially increase growth but ultimately inhibit it.

Anti-androgens are safe and effective for treating moderate to severe adult female acne.

The guide recommends specific methods for diagnosing PCOS and various treatments for its symptoms, while considering the health impacts on adolescents.

The more lipophilic the progesterone derivative, the better it binds to androgen receptors and has antiandrogenic effects.