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Spironolactone, a heart and liver drug, has new uses including cancer treatment, viral infection prevention, and skin condition improvement.

ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.

Men are more likely to have severe respiratory viral infections like COVID-19 due to hormonal and genetic differences, while women generally have stronger immune responses.

Increased PPARGC1α relates to hair thinning in common baldness.

Some sports supplements can cause health issues like mood swings, hair loss, and heart problems in men.

Many adult women suffer from persistent or late-onset acne, and while various treatments exist, finding the right one can be challenging.

Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

PCOS often causes skin issues like excess hair, acne, and hair loss, needing early treatment.

Effective PCOS treatments require targeting specific signaling pathways.

The document concludes that effectively managing PCOS requires a multifaceted approach.

A specific DNA sequence caused hair loss in male mice by activating immune cells and increasing a certain immune signal.

Only minoxidil and finasteride are FDA-approved for hair loss, with other treatments available but less effective or with side effects.

Women with PCOS have more depression and stress due to high androgen levels, not obesity or insulin resistance.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Menopause and aging can affect women's quality of life and sexuality, but hormone therapies may help alleviate these issues.

The conclusion is that there is a high demand for new contraceptives that provide both pregnancy prevention and protection against STIs, along with additional health benefits.

Hair growth is influenced by hormones and goes through different phases; androgens can both promote and inhibit hair growth depending on the body area.

Statins may help treat PCOS by lowering androgen levels and improving cholesterol.

Certain drugs increase calcium levels in cancer cells by triggering internal calcium release.

Androgens play a role in female sexual function, and testosterone therapy can help women with low sexual desire, but more research is needed on treatments and long-term safety.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.

Hair follicle biology advancements may lead to better hair growth disorder treatments.

Blocking the virus's entry into cells by targeting certain pathways could lead to early COVID-19 treatments.

Potassium channel openers like minoxidil help hair grow by acting on hair follicles.

Higher enzyme levels found in women with hair loss, suggesting hormone imbalance.

New hair loss treatments may include topical medications, injections, and improved transplant methods.

Men and women experience skin aging differently due to changes in sex hormone levels with age.

Five preservatives may disrupt hormone function and need more health and environmental risk assessment.